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About Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory condition that generally affects the innermost lining (mucosa) of the large intestine (colon) and rectum. Ulcerative colitis symptoms typically involve the lining becoming inflamed (red and swollen) and tiny open sores (ulcers) forming on the surface of the lining. These ulcers might bleed – in fact, bleeding from the rectum is often a first sign that something’s not quite right. The inflamed lining also produces a larger than normal amount of intestinal lubricant or mucus, which sometimes contains pus. Most people with this condition respond well to colitis treatment, but in more severe cases, surgery may become a necessary path.

How does ulcerative colitis affect the intestines?

Inflammation ‘attacks’ the innermost lining of the colon known as the mucosa, resulting in bleeding and diarrhoea.

The inflammation is most often located in the rectum and lower colon, but can also involve other parts of the colon, sometimes even the entire colon. Less often, it might involve other parts of the intestine. Depending on the exact location of the inflammation, ulcerative colitis is known by other names:

  • Proctitis: involves only the rectum
  • Proctosigmoiditis: involves the rectum and sigmoid colon (the lower segment of the colon before the rectum)
  • Distal colitis: involves only the left side of the colon
  • Pancolitis: involves the entire colon
  • Backwash ileitis: involves the distal ileum.

Additional Information:

The latest news and Research

News

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Posted: January 28 2020

A recent study on a new diet called the IBD-AID diet has shown that it may help. The diet focuses on correcting gut bacteria balance with probiotic and prebiotic foods. “Diet has a huge impact for IBD,” said Dr. David L. Suskind, a gastroenterologist with Seattle Children’s Hospital. He wasn’t involved in the research, but currently studies how […]

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Research

A brief history of human disease genetics

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Genetic discoveries have substantially improved our understanding of the mechanisms responsible for many rare and common diseases and driven development of novel preventative and therapeutic strategies. Medical innovation will increasingly focus on delivering care tailored to individual patterns of genetic predisposition. Main For almost all human diseases, individual susceptibility is, to some degree, influenced by genetic […]

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Crohn’s disease dragged my body to a point where it barely functioned

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What anyone with ulcerative colitis needs to know about colorectal cancer

Posted: January 23 2020

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Research

Adding curcumin to mesalamine may benefit patients with ulcerative colitis

Adjunctive therapy with curcumin was found to provide a greater clinical benefit than placebo in patients with ulcerative colitis (UC) being treated with mesalamine.

To investigate the potential antiinflammatory properties of curcumin, study authors searched various databases (PubMed, EMBASE, Google Scholar, SCOPUS, and Web of Science databases) to obtain randomized controlled trials assessing its use as combination therapy in the treatment of mild to moderate UC. “The outcomes assessed were the pooled odds of clinical response and remission as well […]

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Investigational hyperbaric oxygen therapy (HBOT) indications: inflammatory bowel disease

Posted: January 23 2020

The recent HBOT experience HBOT for ulcerative colitis Until this point, all of the papers have concerned advanced CD, and none have combined UC cases in the mix. Pagoldh et al. designed a prospective, randomized, open-label clinical trial for HBOT intervention and UC, published in 2013. The primary objective of the study was to assess effects […]

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