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About Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory condition that generally affects the innermost lining (mucosa) of the large intestine (colon) and rectum. Ulcerative colitis symptoms typically involve the lining becoming inflamed (red and swollen) and tiny open sores (ulcers) forming on the surface of the lining. These ulcers might bleed – in fact, bleeding from the rectum is often a first sign that something’s not quite right. The inflamed lining also produces a larger than normal amount of intestinal lubricant or mucus, which sometimes contains pus. Most people with this condition respond well to colitis treatment, but in more severe cases, surgery may become a necessary path.

How does ulcerative colitis affect the intestines?

Inflammation ‘attacks’ the innermost lining of the colon known as the mucosa, resulting in bleeding and diarrhoea.

The inflammation is most often located in the rectum and lower colon, but can also involve other parts of the colon, sometimes even the entire colon. Less often, it might involve other parts of the intestine. Depending on the exact location of the inflammation, ulcerative colitis is known by other names:

  • Proctitis: involves only the rectum
  • Proctosigmoiditis: involves the rectum and sigmoid colon (the lower segment of the colon before the rectum)
  • Distal colitis: involves only the left side of the colon
  • Pancolitis: involves the entire colon
  • Backwash ileitis: involves the distal ileum.

Additional Information:

The latest news and Research

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7 Questions every doctor wants you to ask after an ulcerative colitis diagnosis

Posted: July 15 2021

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BiomeBank submits for market authorisation of world first microbial therapy

Posted: July 13 2021

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Kelly Lambert was diagnosed with ulcerative colitis at the age of 19

Posted: July 13 2021

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Sunflower peptide as “template” for potential analgesic

Posted: July 7 2021

That is the finding of an international study led by Christian Gruber from MedUni Vienna’s Institute of Pharmacology (Center for Physiology and Pharmacology), which was conducted jointly with the University of Queensland and Flinders University in Australia and has now been published. The scientific aim of the study is to find analgesics that are only […]

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Personal Story

What I’ve learned about work and Crohn’s disease

Posted: July 6 2021

By Basmah Ali Even though my parents were more flexible with my siblings’ and my career choices, it was still expected for us to study hard and do well. That, along with the Western mentality to value fast-paced work environments, can put a lot of pressure on people with Crohn’s disease such as myself. In my case, I […]

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