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Blog

Sugar may trigger inflammatory bowel disease by breaking down gut mucus

Posted: January 20 2021

By Madeline Barron When I was seventeen, I discovered that I could make s’mores in the microwave. The recipe was simple: slam a marshmallow on to a graham cracker, heat for 20 seconds, and let it balloon. This occasional summer treat soon became a daily indulgence. My inflammatory bowel disease (IBD) diagnosis soon followed.  IBD […]

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Research

Vitamin D modulates intestinal microbiota in inflammatory bowel diseases

The main micronutrient deficiencies observed in patients with IBD are zinc, iron, vitamin B12, and vitamin D, contributing to a critical condition and influencing on well-being.

Inflammatory bowel disease (IBD) is a chronic inflammation of the gastrointestinal tract (GIT), including Crohn’s disease (CD) and ulcerative colitis (UC), which differ in the location and lesion extensions. Both diseases are associated with microbiota dysbiosis, with a reduced populationof butyrate-producing species, abnormal inflammatory response, and micronutrient deficiency (e.g., vitamin D hypovitaminosis). Vitamin D (VitD) […]

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News

Potential preventative treatment demonstrated for Crohn’s disease

Posted: December 22 2020

By Jeff Hansen This research, led by University of Alabama at Birmingham researcher Charles O. Elson, M.D., professor of medicine, focused on a subset of T cells known as T memory, or Tm cells. The UAB researchers used a triple-punch treatment to remove Tm cells and increase the number of T regulatory, or Treg, cells. Both of these results were […]

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News

IBD therapies not linked with adverse pregnancy outcomes

Posted: December 22 2020

Click for Video Link She said they found no association between biologic, thiopurine or combination therapy and adverse outcomes at birth or within the first year of life. Additionally, she said physicians should continue providing IBD medication throughout pregnancy.

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News

Potential new target to combat inflammatory diseases

Posted: December 22 2020

WEHI’s Associate Professor Seth Masters and his research team discovered the compound could prevent upregulation of CD14, a key inflammatory protein. The discovery was recently published in EBioMedicine. At a glance Researchers have uncovered a drug-like compound that blocks a key inflammatory pathway, involving the immune cell protein CD14. In the laboratory, the compound reduced CD14 levels, limiting […]

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Personal Story

‘Invisible and isolating’: Lauren Beasley’s battle with Crohn’s disease

Posted: December 14 2020

The Silver Sands resident has been locked in a fight with the inflammatory bowel disease for the past two years, and as she describes, it has all but brought her life to a standstill. In that time she’s gone from energetic retail worker to unemployed and often bedridden, with both the financial and physical impacts […]

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