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Research

First structure of human protein complex with ‘licence to kill’

A team of WEHI researchers has for the first time visualised a human cell death complex linked to autoimmune and inflammatory conditions, such as inflammatory bowel disease, and injuries associated with excessive cell death.

Using the Australian Synchrotron, the team solved the structure of the human cell death proteins MLKL and RIPK3 bound to each other, as well as human RIPK3 alone. When RIPK3 activates MLKL, it triggers a type of inflammatory cell death called necroptosis that kills the cell and alerts the immune system that it is under attack. However, […]

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Blog

Podcast: My amazing body – Anxiety

Posted: December 20 2021

Listen here. Dr Manaan Kar Ray, a psychiatrist and director for Adult Mental Health at the Princess Alexandra Hospital, explains what anxiety disorder is and how it affects your body. He also talks about the different types of anxiety and the best ways to look after your mental wellbeing. Michelle, a Queensland woman, talks about her lived experience with anxiety. Transcript: Dr Kar Ray: The first thing to […]

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News

‘You never know when you might flare up, day to day life is unpredictable’

Posted: December 13 2021

By Lizzie Thomson Both Crohn’s and colitis can affect anyone, at any age. James was diagnosed with colitis when he was 21. ‘I was vomiting, constantly glued to the toilet and I noticed blood in my stools – I knew something wasn’t right,’ he tells Metro.co.uk. ‘The whole holiday was a shambles for me as […]

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News

Amelia’s story is proof that life can still be good without a large intestine

Posted: December 8 2021

By Amelia Ranger For many, coming up with a Tinder bio is one of the hardest parts of online dating — luckily, I had a good one. ‘I don’t have a large intestine, but I make up for it with personality’. When I was single, my Tinder matches loved to ask me questions about my […]

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Blog

Podcast: Sustainable wellness with Flic Manning

Posted: December 6 2021

Listen here. In this episode spoonie and wellness expert Flic Manning shares with us her personal strategies for navigating treatment, drugs, side effects and B.S. Hear how she interviews clinicians to see if they are the right fit for her! Plus why she shares her experience of Crohn’s disease publicly and without shame. About Flic Flic Manning […]

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Blog

How I cope with eating around the holidays and living with IBD

Posted: December 6 2021

By Rachel Dyckman, RDN As someone with ulcerative colitis, I used to dread holiday gatherings, with their heavy, hard-to-digest meals and abundance of alcoholic beverages. The fact that I couldn’t control what foods were served — coupled with uncertainty about bathroom access and feeling chronically fatigued — sounded like a recipe for disaster. During holiday seasons when […]

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Research

COVID-19 vaccine and IBD

Patients with inflammatory bowel disease (IBD) are frequently treated with immunosuppressive medications.

By Associate Professor Britt Christensen  Key Messages People with IBD are unlikely to be at increased risk of being infected with COVID-19 or developing serious health issues if they are infected with the virus. People using strong corticosteroids to manage Crohn’s or colitis are more likely to have health complications if they are infected with […]

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Blog

How to best support an exercise routine with IBD

Posted: December 5 2021

By Claudia Cramer There are also other challenges with having IBD which may be more invisible to the outside eye, and that is the mental toll of having a chronic disease. Mental health conditions such as depression and anxiety are more common in people with UC and Crohn’s disease than the normal population. This makes […]

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Personal Story

What moving to South Korea taught me about managing life and health with IBD

Posted: December 3 2021

By Sarah Breann Dinwiddie When the blogs I read warned there would be no central air, they didn’t lie. I shoved my face into a handheld fan, sweat dripping, a lanyard with my name on it hanging around my neck. It was 2018, I had been living with Crohn’s disease for over a decade, and I was […]

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