Skip to main content

Ulcerative Colitis Diagnosis

How is ulcerative colitis diagnosed?

Ulcerative colitis is suspected when someone has a history of rectal bleeding (without or without abdominal pain and diarrhoea, which are common ulcerative colitis symptoms). To arrive at a definitive diagnosis, medical practitioners need to investigate in order to eliminate other possibilities (e.g., Crohn’s disease, colorectal cancer).

The medical investigation will include:

  • complete personal medical history, including full review of all symptoms
  • complete family history
  • physical examination
  • examination of stool samples to rule out infectious diseases or check for blood in the stool
  • complete blood count (CBC) or full blood count (FBC), which can provide additional clues to one’s overall health. For example, low levels of red blood cells can suggest internal bleeding and the presence of anaemia. A high white blood cell count, a higher-than-normal level of C-reactive protein (CRP), or a high erythrocyte sedimentation rate (ESR) can indicate the presence of inflammation somewhere in the body
  • direct inspection of intestinal mucosa via endoscopy, including:

    • sigmoidoscopy if examination is limited to the rectum and sigmoid colon
    • colonoscopy if the entire colon is viewed.

 

Additional Information:

The latest news and Research

News

Cure found for rare form of inflammatory bowel disease

Posted: October 18 2020

The disease, called G6PC3 deficiency, affects around one in a million people and causes inflammation of the bowel, as well as lung infections. The team also showed that in affected patients, white blood cells called neutrophils trigger inflammation when exposed to gut bacteria, despite treatment with commonly available biological therapies. The patients were treated at the Royal […]

Read more

News

Team develops wearable sensor to help those with inflammatory bowel disease

Posted: October 12 2020

University of Texas at Dallas researchers have designed a wearable device that monitors sweat for biomarkers that could signal flare-ups of inflammatory bowel disease (IBD). A team of bioengineers demonstrated the wristwatch-like device in a proof-of-concept study funded by the Crohn’s & Colitis Foundation and published online July 28 and in the October print edition […]

Read more

Research

Prevalence of irritable bowel syndrome-type symptoms in patients with inflammatory bowel disease in remission

A systematic review and meta-analysis

Summary Background Patients with inflammatory bowel disease (IBD) often report symptoms compatible with irritable bowel syndrome (IBS), which might have an effect on psychological health. However, previous estimates of the magnitude of this issue have not accounted for ongoing inflammation as the potential cause. We updated a previous systematic review and meta-analysis to determine prevalence […]

Read more

Research

The association between inflammatory potential of diet and disease activity

Results from a cross-sectional study in patients with inflammatory bowel disease

Abstract Background Diet may play a role in disease status in patients with inflammatory bowel disease. We tested whether the inflammatory potential of diet, based on a summation of pro- and anti-inflammatory nutrients, is associated with disease activity in patients with Crohn’s disease and ulcerative colitis. Methods Participants completed a disease activity questionnaire (short Crohn’s […]

Read more

News

What is brain fog and what causes it?

Posted: October 7 2020

Having difficulty concentrating. Feeling confused or forgetful. An inability to focus. Slow thinking or not thinking clearly. A kind of haziness or mental fatigue. Any one of these symptoms can be described as brain fog, says clinical neuropsychologist Caroline Gurvich of Monash University, whose research focuses on cognition and women’s mental health. But although it’s […]

Read more

Research

Cell therapy designed to treat inflammatory bowel disease

The research by the UPV/EHU-University of the Basque Country, in collaboration with Harvard University, has yielded highly encouraging results, and studies in animal models have already begun

The UPV/EHU’s NanoBioCel research group has for many years been developing systems enabling cells to be used as drugs. Cell therapy raises hopes for treating those diseases for which there are as yet no effective pharmacological solutions. Biomaterials, a leading journal in the field of materials sciences and medicine, has just published the paper ‘Multifunctional […]

Read more