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Potential new target to combat inflammatory diseases

Posted: December 22 2020

WEHI’s Associate Professor Seth Masters and his research team discovered the compound could prevent upregulation of CD14, a key inflammatory protein. The discovery was recently published in EBioMedicine. At a glance Researchers have uncovered a drug-like compound that blocks a key inflammatory pathway, involving the immune cell protein CD14. In the laboratory, the compound reduced CD14 levels, limiting […]

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Early, tight control of Crohn’s disease may have lasting benefits

Posted: October 26 2020

Early approaches to treatment of Crohn’s disease followed a step-up algorithm in which the newer medications would only be used if the patient did not benefit from established therapies. This sequential approach — termed step therapy — has more recently been called into question, as studies have repeatedly shown that the newer drugs for Crohn’s […]

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