News
New potential therapy for Crohn’s disease in children
Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn’s disease. This approach could become an alternative to biologic antibody therapies that carry many side effects, including increased risk of certain cancers. […]
Blog
I’m a nutritionist with IBD. These are my 5 favorite foods for gut health
By Alexa Federico While there’s not a singular list of foods that everyone with IBD should toss in their grocery carts (food tolerances vary across the board), there are a handful of foods that stand out as my personal favorites for great gut health. Bone broth Bone broth is a food with ancient origins. It’s made by […]
News
Fungi in the gut prime immunity against infection
Common fungi, often present in the gut, teach the immune system how to respond to their more dangerous relatives, according to new research from scientists at Weill Cornell Medicine. Breakdowns in this process can leave people susceptible to deadly fungal infections. The study, published Feb. 5 in Cell, reveals a new twist in the complex relationship […]
News
Study identifies ‘Achilles heel’ of bacteria linked to Crohn’s disease
In a study published Feb. 3 in Cell Host and Microbe, the investigators showed that patients with Crohn’s disease have an overabundance of a type of gut bacteria called adherent-invasive Escherichia coli (AIEC), whichpromotes inflammation in the intestine. Their experiments revealed that a metabolite produced by the bacteria interacts with immune system cells in the lining of […]
News
Scientists switch on tissue repair in inflammatory bowel disease
When functioning correctly, the immune system protects against harmful agents such as bacteria that get into the body. But in conditions such as inflammatory bowel disease (IBD), the immune system attacks the tissues that line the gut, forming ulcers and causing pain and discomfort. Nearly 3.9 million women and 3.0 million men are living with […]
Blog
Why spending time around other living things positively affects your health
By Markham Heid. How our environments rub off on us, sometimes literally Since 1989, when an American immunologist named David Strachan first introduced it, the “hygiene hypothesis” has gained attention and momentum. In its original form, the hypothesis held that early childhood exposure to germs — meaning infection- or illness-causing microbes — could protect people from […]
Research
International perspectives on management of inflammatory bowel disease
Abstract Background Inflammatory bowel diseases (IBD), including Crohn disease (CD) and ulcerative colitis (UC), are complex disorders with multiple comorbidities. We conducted international patient and physician surveys to evaluate current experiences and perceptions of patients with CD or UC and physicians who treat IBD. Methods The IBD Global Assessment of Patient and Physician Unmet Need […]
News
‘Creeping Fat’ in Crohn’s patients linked to bacteria
In many patients with Crohn’s disease abdominal fat migrates to the wall of the inflamed small intestines. What prompts the fat tissue to “creep” through the abdomen and wrap around the intestines of many patients with this inflammatory bowel disease (IBD) has been an enduring mystery. Now, investigators have identified a critical clue. In a study […]
Research
Opening a new door into kinder, gentler therapies for chronic inflammation
Biologic treatments that have been developed over the past quarter-century have proved to be game-changers, but the drugs are imperfect and leave some patients vulnerable to opportunistic infections, and in rare instances, cancers of the blood. Clearly, there is room for improvement, immunologists worldwide contend. The newly identified antibody is noteworthy because of its activity […]
News
First-line treatment with infliximab versus conventional treatment
Abstract Objective In newly diagnosed paediatric patients with moderate-to-severe Crohn’s disease (CD), infliximab (IFX) is initiated once exclusive enteral nutrition (EEN), corticosteroid and immunomodulator therapies have failed. We aimed to investigate whether starting first-line IFX (FL-IFX) is more effective to achieve and maintain remission than conventional treatment. Design In this multicentre open-label randomised controlled trial, untreated patients […]
Latest Articles
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NewsNew potential therapy for Crohn’s disease in children
Anti-inflammatory nanotherapy produced promising results in a rodent model -
Personal Story‘After my inflammatory bowel disease diagnosis, no one could’ve prepared me for life as a sick mom
Brooke Abbott created IBD Moms to provide support and community for women in her shoes. -
BlogI’m a nutritionist with IBD. These are my 5 favorite foods for gut health
The million-dollar question with inflammatory bowel disease (IBD): “What should I eat?”
