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Advancing research of inflammatory intestinal diseases

Posted: May 10 2021

By Anna MacDonald To help advance research of inflammatory intestinal diseases, Emulate recently launched the Colon Intestine-Chip, a comprehensive model that incorporates human colonic organoids and supportive colonic endothelial cells. We spoke to Dr Lorna Ewart, Emulate’s executive vice president of science, to learn more about the limitations of traditional inflammatory intestinal disease models, what makes the […]

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Blog

Questions people with ulcerative colitis may have about biologics

Posted: February 18 2021

By Korin Miller For some people with ulcerative colitis, biologics are important for managing many painful symptoms, like diarrhea, abdominal pain, and fevers. First, here’s a little refresher on why these symptoms occur in the first place. Ulcerative colitis, an inflammatory bowel disease, causes inflammation and ulcers in your colon and rectum; your specific symptoms may vary depending on where […]

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Research

Opening a new door into kinder, gentler therapies for chronic inflammation

A naturally occurring antibody capable of stimulating the body's immune-suppressing regulatory T cells has been discovered by a team of Harvard scientists.

Biologic treatments that have been developed over the past quarter-century have proved to be game-changers, but the drugs are imperfect and leave some patients vulnerable to opportunistic infections, and in rare instances, cancers of the blood. Clearly, there is room for improvement, immunologists worldwide contend. The newly identified antibody is noteworthy because of its activity […]

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