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Is Crohn’s disease considered an autoimmune disease?


Whether Crohn’s can be considered an autoimmune disease remains unclear.

By Jacquelyn Cafasso 

Crohn’s disease is a type of inflammatory bowel disease (IBD). People with Crohn’s disease experience inflammation in their gastrointestinal tract, most commonly in the small and large intestines. This causes symptoms such as diarrhea, stomach cramps, bloody stool, fever, and weight loss.

An autoimmune disease happens when your immune system attacks healthy cells in your body.

Some people hypothesize that in Crohn’s disease, the immune system is attacking healthy cells of the digestive tract or the bacteria naturally present in the digestive tract.

We’ll dive in and look at what the research shows and what additional data we need to answer this question.

Is Crohn’s an autoimmune disease?

The immune system protects the body against foreign invaders, like viruses, bacteria, and parasites. When these harmful invaders enter the body, the immune system identifies them and launches an attack to eliminate the threat.

An autoimmune disorder is when the body’s immune system mistakenly attacks healthy cells of the body. This often results in inflammation.

Although the immune system is thought to be involved in Crohn’s, the disease isn’t classified as an autoimmune disorder. In fact, the exact cause of Crohn’s disease is still not completely understood.

The researchTrusted Source suggests that the immune system is launching some sort of inappropriate response in people with Crohn’s disease.

However, the current evidence isn’t strong enough to prove that the body is creating antibodies against itself. Crohn’s disease also fails to meet the current standard criteria for classification as an autoimmune disorder.

Posted on: October 29 2021

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