News
Potential preventative treatment demonstrated for Crohn’s disease
By Jeff Hansen This research, led by University of Alabama at Birmingham researcher Charles O. Elson, M.D., professor of medicine, focused on a subset of T cells known as T memory, or Tm cells. The UAB researchers used a triple-punch treatment to remove Tm cells and increase the number of T regulatory, or Treg, cells. Both of these results were […]
News
IBD therapies not linked with adverse pregnancy outcomes
Click for Video Link She said they found no association between biologic, thiopurine or combination therapy and adverse outcomes at birth or within the first year of life. Additionally, she said physicians should continue providing IBD medication throughout pregnancy.
News
Potential new target to combat inflammatory diseases
WEHI’s Associate Professor Seth Masters and his research team discovered the compound could prevent upregulation of CD14, a key inflammatory protein. The discovery was recently published in EBioMedicine. At a glance Researchers have uncovered a drug-like compound that blocks a key inflammatory pathway, involving the immune cell protein CD14. In the laboratory, the compound reduced CD14 levels, limiting […]
Personal Story
‘Invisible and isolating’: Lauren Beasley’s battle with Crohn’s disease
The Silver Sands resident has been locked in a fight with the inflammatory bowel disease for the past two years, and as she describes, it has all but brought her life to a standstill. In that time she’s gone from energetic retail worker to unemployed and often bedridden, with both the financial and physical impacts […]
News
Gut research identifies key cellular changes associated with childhood-onset Crohn’s Disease
The results are an important step towards better management and treatment of this devastating condition. The research from the University of Cambridge and the Wellcome Sanger Institute is part of the global Human Cell Atlas initiative to map every cell type in the human body. The findings reveal intricate cellular mechanisms of how the gut […]
Personal Story
My chronic illness was only taken seriously when it made me thin
By Hattie Gladwell “You look so poorly, you poor thing,” friends and relatives would say as a concerned look spread across their faces. I was 19 and had just been diagnosed with ulcerative colitis, a form of inflammatory bowel disease. I’d been underweight for years and the disease became so severe that it perforated my bowel. Because […]
Blog
Why don’t we take mental pain as seriously as we take physical pain?
By Mark D Rego One of the first patients I saw in medical school was an elderly man dying of metastatic colon cancer, which had spread to his bones and was excruciatingly painful. I was shocked and heartbroken when I saw him beg the doctor for more pain medicine than the modest doses he was […]
Research
Vitamin D regulates calcium in intestine differently than previously thought
In a healthy person, the body absorbs calcium to maintain strong bones and perform other important functions like helping muscles move and nerves carry messages between the brain and body parts. Vitamin D is critical for this calcium absorption from the intestine and for the function of the intestine. The study, published in the journal […]
Blog
Things to do when you’re feeling defeated by inflammatory bowel disease
Finding your perfect treatment and lifestyle combination is like putting together a puzzle. Finding a piece that fits is exciting, but sometimes it feels like you try piece after piece that does not fit. A few of these “puzzle pieces” are: finding a treatment plan that works long term figuring out the best diet for […]
Research
A large proportion of IBD patients may experience a form of PTSD
About a third of inflammatory bowel disease (IBD) patients surveyed were found to meet the clinical threshold to warrant a further diagnosis of post-traumatic stress disorder (PTSD). Alexandra F. Vanderwerff, PhD, Counseling Psychology, University of Memphis, conducted a study examining the prevalence of PTSD symptoms among IBD patients. She explained to HCPLive® that her initial hypothesis centered […]