Skip to main content

Research

News

BiomeBank submits for market authorisation of world first microbial therapy

Posted: July 13 2021

South Australian based biotechnology company BiomeBank has submitted for Market Authorisation of their product for the treatment of recurrent Clostridioides difficile (C-diff) and ulcerative colitis in a bid to meet unmet medical need across Asia Pacific. The drug product is already used in Australia to treat C-diff through faecal microbiota transplantation (FMT) and has been […]

Read more

News

Sunflower peptide as “template” for potential analgesic

Posted: July 7 2021

That is the finding of an international study led by Christian Gruber from MedUni Vienna’s Institute of Pharmacology (Center for Physiology and Pharmacology), which was conducted jointly with the University of Queensland and Flinders University in Australia and has now been published. The scientific aim of the study is to find analgesics that are only […]

Read more

Research

Treating inflammatory bowel disease in mice with engineered probiotic

Researchers from Brigham and Women’s Hospital report they have developed an engineered yeast that can induce multiple effects for treating IBD.

Their findings are published in Nature Medicine in a paper titled, “Self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease.” “IBD is a complex chronic inflammatory disorder of the gastrointestinal tract,” wrote the researchers. “Extracellular adenosine triphosphate (eATP) produced by the commensal microbiota and host cells activates purinergic signaling, promoting intestinal inflammation and pathology. Based […]

Read more

News

Stents inspired by paper-cutting art can deliver drugs to the GI tract

Posted: June 28 2021

By Anne Trafton | MIT News Office Inspired by kirigami, the Japanese art of folding and cutting paper to create three-dimensional structures, MIT engineers and their collaborators have designed a new type of stent that could be used to deliver drugs to the gastrointestinal tract, respiratory tract, or other tubular organs in the body. The stents are […]

Read more

News

Stopping the onset and progression of intractable immune diseases

Posted: June 28 2021

The development of therapeutic drugs for inflammatory bowel disease, an intractable immune disease, and multiple sclerosis – an autoimmune disorder – is gaining traction. A research team from the Department of Life Sciences at POSTECH and a joint research team at ImmunoBiome Inc. have uncovered that a yeast-derived polysaccharide mixture inhibits the onset and progression of immune […]

Read more

Research

Posttraumatic stress symptoms afflict patients with IBD

Survey results supported prior research that found one-quarter to one-third of patients with inflammatory bowel diseases report posttraumatic stress symptoms linked to their disease experience.

By Kate Burba To better characterize posttraumatic stress (PTS) in patients with IBD, researchers surveyed 797 patients registered with the Crohn’s and Colitis Foundation/University of North Carolina IBD Partners database (Crohn’s disease n = 452; ulcerative colitis n = 345). The Post Traumatic Stress Disorder Checklist-5th edition supplemented this survey. According to study results, 5.6% […]

Read more

Blog

Getting enough vitamin D?

Posted: June 21 2021

By  Rus Hughes What is Vitamin D Deficiency? ClevelandClinic.org says that the idea of vitamin D deficiency indicates that an individual does not have sufficient vitamin D in their blood. The same source says that “Vitamin D is unique because your skin actually produces it by using sunlight.” Adding, “Fair-skinned individuals and those who are […]

Read more

News

What diet is most likely to help ease Crohn’s disease?

Posted: June 17 2021

By Cara Murez The study evaluated one of the commonly used diets for Crohn’s disease, known as the specific carbohydrate diet (SCD), comparing it with the Mediterranean diet, which is sometimes recommended by doctors for its heart health benefits, but not for inflammatory bowel diseases like Crohn’s. The scientists found that both diets reduced symptoms […]

Read more

News

Study finds COVID-19 vaccines safe for IBD patients

Posted: June 15 2021

Patients with inflammatory bowel diseases (IBD) do not appear to have increased risk of side effects from the Pfizer or Moderna COVID-19 vaccines, according to a recent Cedars-Sinai study published online and upcoming in print in the American Journal of Gastroenterology. In fact, those being treated with advanced immune-modifying therapies may experience them less often than the general population. IBDs, […]

Read more

News

‘Good’ bacteria show promise for clinical treatment of Crohn’s disease and ulcerative colitis

Posted: June 7 2021

A new study published in Nature Communications demonstrates that a consortium of bacteria designed to complement missing or underrepresented functions in the imbalanced microbiome of inflammatory bowel disease (IBD) patients, prevented and treated chronic immune-mediated colitis in humanized mouse models. The study’s senior author, Balfour Sartor, MD, Midget Distinguished Professor of Medicine, Microbiology and Immunology, Co-Director of the UNC Multidisciplinary […]

Read more