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Walnuts show ability to protect against Ulcerative colitis

Walnuts contain a complex array of natural compounds and phytochemicals that exhibit a wide range of health benefits, including protection against inflammation and colon cancer.

Dietary supplementation with nuts has shown a variety of health benefits. Among the tree nuts, walnuts (Juglans regia) contain the highest levels of the omega-3 fatty acid, namely alpha-linoleic acid (ALA), with the most favorable ratio of omega-3:omega-6 fatty acids (1:4.2) [1]. Walnuts also contain a large number of phytochemicals, including phenolic antioxidants, and high […]

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Smoking and ulcerative colitis

Posted: August 9 2019

Because smokers are less likely to develop ulcerative colitis (UC), a type of inflammatory bowel disease, patients with UC may be tempted to start smoking to lessen their symptoms. Researchers found no beneficial effects of smoking, however, in a nationwide study that included 6,754 patients with UC. Read full article at https://www.news-medical.net/news/20190807/Study-evaluates-the-effect-of-smoking-status-on-disease-outcomes-in-ulcerative-colitis.aspx

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Potential new treatment target for Crohn’s disease

Posted: August 9 2019

Fabio Cominelli, MD, professor of medicine at the School of Medicine and chief of gastroenterology at University Hospitals Cleveland Medical Center, led a three-year study, published recently in Cellular and Molecular Gastroenterology and Hepatology, focusing on the chronic inflammation that occurs in genetically susceptible individuals with CD. Using mouse models of CD, Cominelli and his team […]

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Editing of gut bacteria reduces cancer in mice with colitis

Posted: August 3 2019

Researchers have found that editing of the genes of the bacteria present in the guts of mice could help reduce the inflammation and associated risk of colorectal cancers. The research from the UT Southwestern scientists has been published this week in the latest issue of the Journal of Experimental Medicine. The study is titled, “Editing of […]

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How do Interactions between Gut Bacteria and Fungi Exacerbate Crohn’s Disease?

Posted: July 27 2019

Scientists have known that bacteria in the gut, along with environmental and genetic factors, contribute to the debilitating intestinal ailment of Crohn’s disease (CD). But in 2016, Mahmoud A Ghannoum, PhD, FAAM, FIDSA, professor and director of the Center for Medical Mycology at Case Western Reserve School of Medicine and University Hospitals Cleveland Medical Center, […]

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Crohn’s Disease Remission with a Plant-Based Diet: A Case Report

Posted: July 8 2019

In November 2014, a 25-year-old-male presented to the Department of Gastroenterology at a secondary care facility after having experienced several months of weight loss, diarrhea, and flu-like symptoms. He had a past medical history of peri-anal abscess and was on no prescribed or over-the-counter medications. He was a non-smoker. Ileo-colonoscopy demonstrated moderately inflamed mucosa with […]

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New study helps develop treatments targeting inflammation without affecting gut function

Posted: June 28 2019

A new Crick-led study in Immunity has characterized these distinct populations, which could help scientists to develop treatments targeting inflammation while preserving healthy gut function. These two populations are akin to worker and soldier ants, playing different roles depending on their context. The ‘worker ant’ population of immune cells is found naturally in the gut and helps […]

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Mass cytometry distinguishes between Crohn’s disease and Ulcerative colitis

Identification of better markers using less invasive methods would enable earlier diagnosis as well as improved monitoring and treatment of both diseases.

CD and UC can be distinguished clinically by disease location (UC is restricted to the colon, while CD can involve any part of the gastrointestinal tract) and disease phenotype (stricturing or penetrating can indicate CD), using endoscopy and imaging5. However, gathering this information can be invasive and costly, and still up to 20% of IBD […]

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Inflammatory bowel disease and type I diabetes increase chances of developing rheumatoid arthritis

Posted: June 18 2019

RA is a chronic inflammatory disease that affects the joints, causing pain and disability. It can also affect internal organs. RA is more common in older people, but there is also a high prevalence in young adults, adolescents and even children, and it affects women more frequently than men. IBD is an umbrella term used […]

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A single gut enterotype linked to both inflammatory bowel disease and depression

Posted: June 18 2019

In 2012, Professor Jeroen Raes (VIB-KU Leuven Center for Microbiology) launched the Flemish Gut Flora Project. Sequencing fecal samples of over 3,000 healthy volunteers, Prof. Raes and his team defined the boundaries of a normal, health-associated gut microbiota. Next, the team turned to patient groups to identify microbiome alterations associated with diseases. Recently, they described […]

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