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Cure found for rare form of inflammatory bowel disease

Posted: October 18 2020

The disease, called G6PC3 deficiency, affects around one in a million people and causes inflammation of the bowel, as well as lung infections. The team also showed that in affected patients, white blood cells called neutrophils trigger inflammation when exposed to gut bacteria, despite treatment with commonly available biological therapies. The patients were treated at the Royal […]

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News

Team develops wearable sensor to help those with inflammatory bowel disease

Posted: October 12 2020

University of Texas at Dallas researchers have designed a wearable device that monitors sweat for biomarkers that could signal flare-ups of inflammatory bowel disease (IBD). A team of bioengineers demonstrated the wristwatch-like device in a proof-of-concept study funded by the Crohn’s & Colitis Foundation and published online July 28 and in the October print edition […]

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Research

Cell therapy designed to treat inflammatory bowel disease

The research by the UPV/EHU-University of the Basque Country, in collaboration with Harvard University, has yielded highly encouraging results, and studies in animal models have already begun

The UPV/EHU’s NanoBioCel research group has for many years been developing systems enabling cells to be used as drugs. Cell therapy raises hopes for treating those diseases for which there are as yet no effective pharmacological solutions. Biomaterials, a leading journal in the field of materials sciences and medicine, has just published the paper ‘Multifunctional […]

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News

Blueberry compound may provide new inflammatory bowel disease therapy

Posted: October 5 2020

They believe it can provide a potential therapeutic option for chronic inflammatory diseases, including inflammatory bowel disease (IBD). The team, led by Chiharu Nishiyama, PhD, published its study “Pterostilbene reduces colonic inflammation by suppressing dendritic cell activation and promoting regulatory T cell development” in The FASEB Journal. The compound is similar to another phytocompound known to […]

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Research

Rare immune cells drive gut repair

But can tip toward cancer or fibrosis in inflammatory bowel disease.

A team of scientists, led by King’s College London, have discovered an unexpected tissue reparative role for a rare immune cell type in the gut that could tip toward fibrosis or cancer if abnormal or impaired. The breakthrough, revealed in a paper published in Nature Materials, will have important implications for treating patients who suffer from […]

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Research

Immune cells sculpt circuits in the brain

Brain immune cells, called microglia, protect the brain from infection and inflammation. It turns out that they also sculpt circuits in the developing brain in response to sensory cues.

Immune cells play an unexpected role in fine-tuning the brain’s neural circuits, according to research published in September, 2020 in Neuron. The immune cells that reside there, known as microglia, not only protect the brain from infection and inflammation, they also help physically sculpt circuits in the developing brain. The new work demonstrates that microglia also […]

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News

Lack of treatment compromising NZ patients

Posted: September 10 2020

Senior Clinical Nurse specialists caring for some of New Zealand’s sickest bowel disease patients say the Government has turned its back on their patients by refusing to fund routine, mainstream treatments that have been in use around the world for the past several years. They say that in denying treatment for these severely ill patients […]

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Research

Review: Probiotics for induction of remission in Crohn’s disease

Probiotics can be used to manipulate the microbiome and have therefore been considered as a potential therapy for CD.

There is some evidence that probiotics benefit other gastrointestinal conditions, such as irritable bowel syndrome and ulcerative colitis, but their efficacy in CD is unclear. This is the first update of a Cochrane Review previously published in 2008. Read the full review here.

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News

11 Medicine cabinet essentials for people with Crohn’s

Posted: August 17 2020

If you have Crohn’s disease, your medicine cabinet is probably well stocked with prescription medications, including immunosuppressants, antibiotics, and anti-inflammatories, such as corticosteroids. But it’s also a good idea to keep several over-the-counter (OTC) medicines and supplies on hand in case of an emergency. Keep these essential nonprescription supplies at home to ease your symptoms and […]

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News

Do probiotics actually do anything

Posted: August 10 2020

There is an invisible universe hidden inside your body, it’s called the gut microbiome — a vast array of trillions of intestinal bacteria, hundreds of different species. They help digest your food in exchange for a warm, safe place to live. And we are only now starting to discover the gut microbiome plays a much […]

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