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Unique imaging technology to map cells tied to inflammatory bowel disease

Posted: September 24 2021

New “maps” of hundreds of thousands of cells related to inflammatory bowel disease shed greater light on their effects on intestinal tissues through a newly utilized imaging technique called “imaging mass cytometry.” The novel findings by researchers at the Perelman School of Medicine at the University of Pennsylvania provide a possible path to better targeted […]

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News

Statins may be effective treatment for patients with ulcerative colitis

Posted: September 23 2021

By Hanae Armitage There may be good news for the nearly 1 million people battling ulcerative colitis, a type of inflammatory bowel condition with no real cure: Statins, a commonly prescribed cholesterol-lowering drug, seem to be an effective, if unexpected, treatment for the condition, according to a new Stanford Medicine study. Currently, the only lines of defense […]

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Blog

Here’s how Crohn’s disease can affect your eyes

Posted: September 17 2021

By Leandra Beabout  Some folks might experience sensitivity to light during a flare-up. But can your gut actually mess with your vision? Is there a link between Crohn’s disease and your eyes? It turns out, your body parts might be more interconnected than you think. Can Crohn’s disease really affect your eyes? For some folks, yes! Crohn’s is classified as […]

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Research

Novel mechanism links genetic defect in IBD patients to gut leakiness

UC Riverside-led study in mice and human tissue is the first to show how a disease mutation weakens barrier properties of epithelial cells lining the gut

By Iqbal Pittalwala A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier. The intestinal epithelium, a single layer […]

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News

Precursor to ulcerative colitis in healthy individuals years before onset of disease

Posted: September 10 2021

By Maria Elisson Ulcerative colitis is an inflammatory bowel disease (IBD), with symptoms normally setting in between late adolescence and the age of 30. What causes it is not yet known, but there is lots to suggest that the disease is a result of an interplay between genetic and environmental factors and that gut flora […]

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Research

Risk factors associated with inflammatory owel Disease

Expert gastroenterologists review the pathophysiology of inflammatory bowel disease (IBD) along with the associated risk factors.

Remo Panaccione, MD, FRCPC, Jessica Allegretti, MD, MPH, Edward Loftus Jr., MD, William Sandborn, MD Watch video here. Transcript: Remo Panaccione, MD, FRCPC: Hello, and welcome to this HCPLive® Peer Exchange titled “Optimizing Treatment Strategies to Manage Inflammatory Bowel disease.” I’m Dr Remo Panaccione, a professor of medicine at the Cumming School of Medicine at the University of Calgary in Calgary, Canada. […]

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News

Crohn’s and colitis: Could an antifungal vaccine relieve symptoms?

Posted: July 26 2021

By James Kingsland The human gut is home to an extraordinarily diverse community of bacteria, viruses, archaea, and fungi. Usually, these microorganisms live harmoniously with their human hosts in complex, mutually beneficial relationships. These alliances are disrupted by health conditions that involve inflammation of the gut, however. For example, research suggests that certain fungal species that are harmless […]

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News

BiomeBank submits for market authorisation of world first microbial therapy

Posted: July 13 2021

South Australian based biotechnology company BiomeBank has submitted for Market Authorisation of their product for the treatment of recurrent Clostridioides difficile (C-diff) and ulcerative colitis in a bid to meet unmet medical need across Asia Pacific. The drug product is already used in Australia to treat C-diff through faecal microbiota transplantation (FMT) and has been […]

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Personal Story

Kelly Lambert was diagnosed with ulcerative colitis at the age of 19

Posted: July 13 2021

By Brendan Crabb After being diagnosed at the age of 19, for many years afterwards Mrs Lambert had to constantly be conscious of where the nearest bathroom was located. “The disease totally dominated my life for a good five years,” the 46-year-old said. “It struck me down… It stopped me from doing a lot of […]

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News

Sunflower peptide as “template” for potential analgesic

Posted: July 7 2021

That is the finding of an international study led by Christian Gruber from MedUni Vienna’s Institute of Pharmacology (Center for Physiology and Pharmacology), which was conducted jointly with the University of Queensland and Flinders University in Australia and has now been published. The scientific aim of the study is to find analgesics that are only […]

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