News
Potential preventative treatment demonstrated for Crohn’s disease
By Jeff Hansen This research, led by University of Alabama at Birmingham researcher Charles O. Elson, M.D., professor of medicine, focused on a subset of T cells known as T memory, or Tm cells. The UAB researchers used a triple-punch treatment to remove Tm cells and increase the number of T regulatory, or Treg, cells. Both of these results were […]
News
Potential new target to combat inflammatory diseases
WEHI’s Associate Professor Seth Masters and his research team discovered the compound could prevent upregulation of CD14, a key inflammatory protein. The discovery was recently published in EBioMedicine. At a glance Researchers have uncovered a drug-like compound that blocks a key inflammatory pathway, involving the immune cell protein CD14. In the laboratory, the compound reduced CD14 levels, limiting […]
Research
Vitamin D regulates calcium in intestine differently than previously thought
In a healthy person, the body absorbs calcium to maintain strong bones and perform other important functions like helping muscles move and nerves carry messages between the brain and body parts. Vitamin D is critical for this calcium absorption from the intestine and for the function of the intestine. The study, published in the journal […]
Personal Story
Teen’s Crohn’s treatment helps her keep playing music
For Abigail Tucker, it started with migraines and stomach pains. Then she started losing weight — as much as 50 pounds. She said her condition worsened to the point that, when she was 13, she felt like withdrawing from friends and skipping activities such as playing or teaching piano. Soon she was often missing a […]
News
Severe form of inflammatory bowel disease linked to mouth bacteria
Severe ulcerative colitis – a form of inflammatory bowel disease (IBD) – has been linked to a newly-discovered strain of oral bacteria, a study led by UNSW Sydney has found. Scientists have discovered a molecule called ‘pSma1’ in bacterial cell samples from people with severe ulcerative colitis. The molecule was found in some strains of […]
News
Early, tight control of Crohn’s disease may have lasting benefits
Early approaches to treatment of Crohn’s disease followed a step-up algorithm in which the newer medications would only be used if the patient did not benefit from established therapies. This sequential approach — termed step therapy — has more recently been called into question, as studies have repeatedly shown that the newer drugs for Crohn’s […]
News
Cure found for rare form of inflammatory bowel disease
The disease, called G6PC3 deficiency, affects around one in a million people and causes inflammation of the bowel, as well as lung infections. The team also showed that in affected patients, white blood cells called neutrophils trigger inflammation when exposed to gut bacteria, despite treatment with commonly available biological therapies. The patients were treated at the Royal […]
News
Team develops wearable sensor to help those with inflammatory bowel disease
University of Texas at Dallas researchers have designed a wearable device that monitors sweat for biomarkers that could signal flare-ups of inflammatory bowel disease (IBD). A team of bioengineers demonstrated the wristwatch-like device in a proof-of-concept study funded by the Crohn’s & Colitis Foundation and published online July 28 and in the October print edition […]
Research
Cell therapy designed to treat inflammatory bowel disease
The UPV/EHU’s NanoBioCel research group has for many years been developing systems enabling cells to be used as drugs. Cell therapy raises hopes for treating those diseases for which there are as yet no effective pharmacological solutions. Biomaterials, a leading journal in the field of materials sciences and medicine, has just published the paper ‘Multifunctional […]
News
Blueberry compound may provide new inflammatory bowel disease therapy
They believe it can provide a potential therapeutic option for chronic inflammatory diseases, including inflammatory bowel disease (IBD). The team, led by Chiharu Nishiyama, PhD, published its study “Pterostilbene reduces colonic inflammation by suppressing dendritic cell activation and promoting regulatory T cell development” in The FASEB Journal. The compound is similar to another phytocompound known to […]
Latest Articles
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BlogSugar may trigger inflammatory bowel disease by breaking down gut mucus
Mice fed sugar-heavy diets have worse colitis and more mucous-degrading gut bacteria -
ResearchVitamin D modulates intestinal microbiota in inflammatory bowel diseases
The main micronutrient deficiencies observed in patients with IBD are zinc, iron, vitamin B12, and vitamin D, contributing to a critical condition and influencing on well-being. -
NewsPotential preventative treatment demonstrated for Crohn’s disease
A potential preventive treatment for Crohn’s disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn’s disease.
