News
For good health, trust your gut
By Michael Miller University of Cincinnati assistant professor Ashley Ross says your body is full of neurons that regulate digestion, inflammation and a host of other biological processes. In her chemistry lab in UC’s College of Arts and Sciences, she is studying the role they play in the immune system. “I’m fascinated by the concept that […]
News
Could a yeast found in cheese be key to easing Crohn’s disease?
Areas of unhealed wounds in the intestines of Crohn’s patients have elevated levels of a type of yeast widely found in cheese and processed meat, the new study found. The researchers discovered that levels of the yeast Debaryomyces hansenii are higher in Crohn’s disease patients than in people without the disease. In Crohn’s patients, levels of the […]
News
Podcast: Faecal microbiota transplantation: indications, evidence and safety
Read the full article in Australian Prescriber. Listen to podcast here. Transcript Welcome to Australian Prescriber Podcast. Australian Prescriber, independent, peer-reviewed, and free. Faecal microbiota transplantation or FMT. At first, it evoked surprise and mirth among some, but that was quickly replaced by the excitement about the possibilities that FMT might bring. It suddenly escalated as a potential […]
News
New potential therapy for Crohn’s disease in children
Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn’s disease. This approach could become an alternative to biologic antibody therapies that carry many side effects, including increased risk of certain cancers. […]
Blog
Questions people with ulcerative colitis may have about biologics
By Korin Miller For some people with ulcerative colitis, biologics are important for managing many painful symptoms, like diarrhea, abdominal pain, and fevers. First, here’s a little refresher on why these symptoms occur in the first place. Ulcerative colitis, an inflammatory bowel disease, causes inflammation and ulcers in your colon and rectum; your specific symptoms may vary depending on where […]
News
Fungi in the gut prime immunity against infection
Common fungi, often present in the gut, teach the immune system how to respond to their more dangerous relatives, according to new research from scientists at Weill Cornell Medicine. Breakdowns in this process can leave people susceptible to deadly fungal infections. The study, published Feb. 5 in Cell, reveals a new twist in the complex relationship […]
News
Study identifies ‘Achilles heel’ of bacteria linked to Crohn’s disease
In a study published Feb. 3 in Cell Host and Microbe, the investigators showed that patients with Crohn’s disease have an overabundance of a type of gut bacteria called adherent-invasive Escherichia coli (AIEC), whichpromotes inflammation in the intestine. Their experiments revealed that a metabolite produced by the bacteria interacts with immune system cells in the lining of […]
News
Scientists switch on tissue repair in inflammatory bowel disease
When functioning correctly, the immune system protects against harmful agents such as bacteria that get into the body. But in conditions such as inflammatory bowel disease (IBD), the immune system attacks the tissues that line the gut, forming ulcers and causing pain and discomfort. Nearly 3.9 million women and 3.0 million men are living with […]
Research
Ulcerative colitis narrative global survey findings
Abstract Background The Ulcerative Colitis (UC) Narrative is a global patient and physician survey aimed at identifying the impact of UC and comparing and contrasting perceptions of UC burden and management approaches. Methods Surveys of patients with UC (self-reported diagnosis; n = 2100) and physicians (n = 1254) were completed across 10 countries by The […]
News
‘Creeping Fat’ in Crohn’s patients linked to bacteria
In many patients with Crohn’s disease abdominal fat migrates to the wall of the inflamed small intestines. What prompts the fat tissue to “creep” through the abdomen and wrap around the intestines of many patients with this inflammatory bowel disease (IBD) has been an enduring mystery. Now, investigators have identified a critical clue. In a study […]
Latest Articles
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ResearchThe gut microbiota and inflammation: An overview
The understanding of the symbiotic relationship between the human gut bacteria and the overall functioning of the body has significantly deepened and broadened, with acceleration in research output concerning this area. -
Personal StoryHow Crohn’s disease helped me become stronger
Imagine being told you have Crohn’s disease at age 16. That’s what happened to me. All I heard was the word “disease.” -
BlogWhy everyone with IBD should be offered therapy
We could all use a little help processing the life changing reality of a serious diagnosis.
