Skip to main content

Medication & Treatment

Research

Walnuts show ability to protect against Ulcerative colitis

Walnuts contain a complex array of natural compounds and phytochemicals that exhibit a wide range of health benefits, including protection against inflammation and colon cancer.

Dietary supplementation with nuts has shown a variety of health benefits. Among the tree nuts, walnuts (Juglans regia) contain the highest levels of the omega-3 fatty acid, namely alpha-linoleic acid (ALA), with the most favorable ratio of omega-3:omega-6 fatty acids (1:4.2) [1]. Walnuts also contain a large number of phytochemicals, including phenolic antioxidants, and high […]

Read more

News

Smoking and ulcerative colitis

Posted: August 9 2019

Because smokers are less likely to develop ulcerative colitis (UC), a type of inflammatory bowel disease, patients with UC may be tempted to start smoking to lessen their symptoms. Researchers found no beneficial effects of smoking, however, in a nationwide study that included 6,754 patients with UC. Read full article at https://www.news-medical.net/news/20190807/Study-evaluates-the-effect-of-smoking-status-on-disease-outcomes-in-ulcerative-colitis.aspx

Read more

News

Potential new treatment target for Crohn’s disease

Posted: August 9 2019

Fabio Cominelli, MD, professor of medicine at the School of Medicine and chief of gastroenterology at University Hospitals Cleveland Medical Center, led a three-year study, published recently in Cellular and Molecular Gastroenterology and Hepatology, focusing on the chronic inflammation that occurs in genetically susceptible individuals with CD. Using mouse models of CD, Cominelli and his team […]

Read more

News

Editing of gut bacteria reduces cancer in mice with colitis

Posted: August 3 2019

Researchers have found that editing of the genes of the bacteria present in the guts of mice could help reduce the inflammation and associated risk of colorectal cancers. The research from the UT Southwestern scientists has been published this week in the latest issue of the Journal of Experimental Medicine. The study is titled, “Editing of […]

Read more

News

How do Interactions between Gut Bacteria and Fungi Exacerbate Crohn’s Disease?

Posted: July 27 2019

Scientists have known that bacteria in the gut, along with environmental and genetic factors, contribute to the debilitating intestinal ailment of Crohn’s disease (CD). But in 2016, Mahmoud A Ghannoum, PhD, FAAM, FIDSA, professor and director of the Center for Medical Mycology at Case Western Reserve School of Medicine and University Hospitals Cleveland Medical Center, […]

Read more

News

New study helps develop treatments targeting inflammation without affecting gut function

Posted: June 28 2019

A new Crick-led study in Immunity has characterized these distinct populations, which could help scientists to develop treatments targeting inflammation while preserving healthy gut function. These two populations are akin to worker and soldier ants, playing different roles depending on their context. The ‘worker ant’ population of immune cells is found naturally in the gut and helps […]

Read more

Research

Mass cytometry distinguishes between Crohn’s disease and Ulcerative colitis

Identification of better markers using less invasive methods would enable earlier diagnosis as well as improved monitoring and treatment of both diseases.

CD and UC can be distinguished clinically by disease location (UC is restricted to the colon, while CD can involve any part of the gastrointestinal tract) and disease phenotype (stricturing or penetrating can indicate CD), using endoscopy and imaging5. However, gathering this information can be invasive and costly, and still up to 20% of IBD […]

Read more

News

Cannabis use in inflammatory bowel disease: new surveys announced

Posted: June 18 2019

Inflammatory Bowel Disease (IBD) is an umbrella term describing chronic and relapsing inflammatory diseases of the gastrointestinal tract, including ulcerative colitis and Crohn’s disease. Affected individuals experience abdominal pain, weight loss, diarrhoea and bleeding with a high risk of developing colorectal and small bowel cancers. It is a debilitating condition that often significantly affects a […]

Read more

News

Daily pill containing gut bacteria from healthy people may help fight incurable conditions

Posted: May 27 2019

Bacteria taken from the faeces of healthy people could be used to treat Alzheimer’s, Parkinson’s and cancer, researchers claim. They hope the bacteria could one day replace potent drugs and treatments such as chemotherapy, which can cause a host of unwanted side effects. British scientists have now started the first trial to test whether taking […]

Read more

Research

Estrogen receptor mediates anti-inflammatory action in Crohn’s disease

Accumulating evidence highlights the meaningful impact of estrogen receptors in physiology and pathophysiology of the colon.

Crohn’s disease (CD) is one of the inflammatory bowel disease (IBD) types characterized by chronic intestine inflammation. Although intestinal microbiota has been identified as the main factor responsible for immune response alternation in the past decade, other factors involved in CD pathogenesis, such as genetic and environmental, have been described. Etiology of CD is still […]

Read more