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For good health, trust your gut

Posted: March 23 2021

By Michael Miller University of Cincinnati assistant professor Ashley Ross says your body is full of neurons that regulate digestion, inflammation and a host of other biological processes. In her chemistry lab in UC’s College of Arts and Sciences, she is studying the role they play in the immune system. “I’m fascinated by the concept that […]

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News

Could a yeast found in cheese be key to easing Crohn’s disease?

Posted: March 22 2021

Areas of unhealed wounds in the intestines of Crohn’s patients have elevated levels of a type of yeast widely found in cheese and processed meat, the new study found. The researchers discovered that levels of the yeast Debaryomyces hansenii are higher in Crohn’s disease patients than in people without the disease. In Crohn’s patients, levels of the […]

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News

Podcast: Faecal microbiota transplantation: indications, evidence and safety

Posted: March 4 2021

Read the full article in Australian Prescriber. Listen to podcast here. Transcript Welcome to Australian Prescriber Podcast. Australian Prescriber, independent, peer-reviewed, and free. Faecal microbiota transplantation or FMT. At first, it evoked surprise and mirth among some, but that was quickly replaced by the excitement about the possibilities that FMT might bring. It suddenly escalated as a potential […]

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News

New potential therapy for Crohn’s disease in children

Posted: February 24 2021

Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn’s disease. This approach could become an alternative to biologic antibody therapies that carry many side effects, including increased risk of certain cancers. […]

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Blog

Questions people with ulcerative colitis may have about biologics

Posted: February 18 2021

By Korin Miller For some people with ulcerative colitis, biologics are important for managing many painful symptoms, like diarrhea, abdominal pain, and fevers. First, here’s a little refresher on why these symptoms occur in the first place. Ulcerative colitis, an inflammatory bowel disease, causes inflammation and ulcers in your colon and rectum; your specific symptoms may vary depending on where […]

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News

Fungi in the gut prime immunity against infection

Posted: February 12 2021

Common fungi, often present in the gut, teach the immune system how to respond to their more dangerous relatives, according to new research from scientists at Weill Cornell Medicine. Breakdowns in this process can leave people susceptible to deadly fungal infections. The study, published Feb. 5 in Cell, reveals a new twist in the complex relationship […]

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News

Study identifies ‘Achilles heel’ of bacteria linked to Crohn’s disease

Posted: February 11 2021

In a study published Feb. 3 in Cell Host and Microbe, the investigators showed that patients with Crohn’s disease have an overabundance of a type of gut bacteria called adherent-invasive Escherichia coli (AIEC), whichpromotes inflammation in the intestine. Their experiments revealed that a metabolite produced by the bacteria interacts with immune system cells in the lining of […]

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News

Scientists switch on tissue repair in inflammatory bowel disease

Posted: February 9 2021

When functioning correctly, the immune system protects against harmful agents such as bacteria that get into the body. But in conditions such as inflammatory bowel disease (IBD), the immune system attacks the tissues that line the gut, forming ulcers and causing pain and discomfort. Nearly 3.9 million women and 3.0 million men are living with […]

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Research

Ulcerative colitis narrative global survey findings

The impact of living with ulcerative colitis—patients’ and physicians’ views.

Abstract Background The Ulcerative Colitis (UC) Narrative is a global patient and physician survey aimed at identifying the impact of UC and comparing and contrasting perceptions of UC burden and management approaches. Methods Surveys of patients with UC (self-reported diagnosis; n = 2100) and physicians (n = 1254) were completed across 10 countries by The […]

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News

‘Creeping Fat’ in Crohn’s patients linked to bacteria

Posted: February 5 2021

In many patients with Crohn’s disease abdominal fat migrates to the wall of the inflamed small intestines. What prompts the fat tissue to “creep” through the abdomen and wrap around the intestines of many patients with this inflammatory bowel disease (IBD) has been an enduring mystery. Now, investigators have identified a critical clue. In a study […]

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