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Kids & Teens

Research

Greenspace exposure during childhood reduces risk for IBD

Childhood exposure to residential greenspace was associated with a reduced risk for inflammatory bowel disease, according to data published in the American Journal of Gastroenterology.

By Monica Stonehill “Intervention studies designed to target specific environmental risk factors to reduce the risk of IBD should include greenspace in study design,” Michael Elten, MSc, from the School of Epidemiology and Public Health, University of Ottawa in Canada, and colleagues wrote. “It is possible that by changing our immediate environment, we could prevent childhood-onset IBD.” Elten and colleagues […]

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News

First-line treatment with infliximab versus conventional treatment

Posted: January 31 2021

Abstract Objective In newly diagnosed paediatric patients with moderate-to-severe Crohn’s disease (CD), infliximab (IFX) is initiated once exclusive enteral nutrition (EEN), corticosteroid and immunomodulator therapies have failed. We aimed to investigate whether starting first-line IFX (FL-IFX) is more effective to achieve and maintain remission than conventional treatment. Design In this multicentre open-label randomised controlled trial, untreated patients […]

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News

Gut research identifies key cellular changes associated with childhood-onset Crohn’s Disease

Posted: December 14 2020

The results are an important step towards better management and treatment of this devastating condition.  The research from the University of Cambridge and the Wellcome Sanger Institute is part of the global Human Cell Atlas initiative to map every cell type in the human body. The findings reveal intricate cellular mechanisms of how the gut […]

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News

Cure found for rare form of inflammatory bowel disease

Posted: October 18 2020

The disease, called G6PC3 deficiency, affects around one in a million people and causes inflammation of the bowel, as well as lung infections. The team also showed that in affected patients, white blood cells called neutrophils trigger inflammation when exposed to gut bacteria, despite treatment with commonly available biological therapies. The patients were treated at the Royal […]

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Research

The psychosocial burden of inflammatory bowel disease in adolescents and young adults

This study examined the psychosocial burden of inflammatory bowel disease (IBD) in young people aged 15‐25 years attending a tertiary specialist health centre for adolescents and young adults in Brisbane.

Methods Young people with IBD provided demographic information and psychosocial data via a cross‐sectional self‐report survey. Psychosocial data included the Kessler Psychological Distress Scale (K‐10), Perceived Stress Scale (PSS‐10), Brief Illness Perception Questionnaire (Brief IPQ), World Health Organisation Wellbeing Index (WHO‐5), Pediatric Quality of Life Inventory (PedsQL), Short Quality of Life Questionnaire for IBD (SIBDQ), […]

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News

“I don’t want my friends to know”

Posted: September 7 2020

Read ‘I don’t want my friends to know’ – young people on growing up with Crohn’s or colitis by Bernie Carter, Alison Rouncefield-Swales and Pamela Qualter. Young people with chronic health conditions cope with all of the usual challenges of growing up – making friends, changing schools, adapting to new situations, developing a sense of self, and dealing with interpersonal conflict. […]

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News

5 major advances in inflammatory bowel disease (IBD) treatment

Posted: January 30 2020

Lymphoma not associated with anti-TNF therapy in pediatric IBD patients Anti-tumor necrosis factor (aTNF) drugs are among the most effective medications used to treat pediatric IBD. Despite their effectiveness, concerns regarding an association with lymphoma limit their use in everyday practice. Based on a large, geographically diverse administrative insurance claims database of 9,284 pediatric IBD […]

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News

Specialised immune cells could help repair inflammatory bowel disease damage in children

Posted: December 17 2019

“This study offers new hope for kids with IBD who urgently need new treatments by showing that Tr1 cells have the potential to reverse the damage caused by IBD,” said senior author Dr. Megan Levings, an investigator and head of the Childhood Disease Research Theme at BC Children’s and a professor in UBC’s department of […]

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News

Exposure to TNF inhibitors increases psoriasis risk in children with IBD, JIA

Posted: November 28 2019

The single-center study of electronic health record data from 2008 to 2018 included 4,403 children under 19 years at diagnosis, each with at least two ICD-9 or ICD-10 codes for JIA, IBD or chronic noninfectious osteomyelitis and at least two visits with a study center rheumatologist or gastroenterologist. Researchers defined TNF inhibitor exposure as at least […]

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Personal Story

Lemonade stand helps fight Cronh’s disease

Posted: November 12 2019

On the Friday before Labor Day, a quiet side street in Canton, Massachusetts, is buzzing with activity. Cars line both sides of the street, and kids ride their bikes back and forth. Local firetrucks and police cars sound their alarms in celebration. In fact, it seems the entire town of Canton has descended upon the […]

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