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Crohn’s Disease

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Antioxidants in corn line could aid human IBD protection, therapy

Posted: July 13 2020

The researchers bred a novel line of corn at Penn State’s Russell E. Larson Agricultural Research Center to produce compounds called flavan-4-ols. The team then conducted an experiment with mice to judge the effect of those powerful antioxidant compounds on induced inflammation of the colon. “In this study, we utilized two corn lines­ – one […]

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Real advice for parenting through UC

Posted: July 6 2020

Plan for Flares “I have a 6-month old, and I recently experienced a severe flare,” says Jamie D., of Chelan, WA. “I knew I was going to need a plan for when I was running to the bathroom 10 times a day on the days my husband was gone. (He’s a firefighter, so I’m home […]

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Research

The microbiome in inflammatory bowel diseases

From pathogenesis to therapy.

Inflammatory bowel disease (IBD) has become a global disease with accelerating incidence worldwide in the 21st century while its accurate etiology remains unclear. In the past decade, gut microbiota dysbiosis has consistently been associated with IBD. Although many IBD-associated dysbiosis have not been proven to be a cause or an effect of IBD, it is […]

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Cloning stem cells to find a cure for Crohn’s disease

Posted: July 6 2020

For over a decade, Wa Xian, research associate professor of biology and biochemistry at the University of Houston Stem Cell Center, has been perfecting technology for cloning stem cells. Now she is using it to take aim at pediatric Crohn’s disease. Xian, who received a $1.9 million grant from the National Institute of Diabetes and […]

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Greater recurrence of CRC in late-onset vs early onset IBD

Posted: June 27 2020

These findings suggest a difference in colorectal cancer pathophysiology by age, according to the researchers. “Despite longer IBD disease duration at the time of colon or rectal cancer diagnosis, patients with early-onset IBD had significantly more advanced colitis at the time of diagnosis of colon and rectal cancer,” Robert Goldstone, MD, Massachusetts General Hospital general and GI surgeon, […]

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‘Important’ microbiome studies offer hope for IBD prediction

Posted: June 26 2020

We may be able to predict disease relapse in patients with chronic inflammatory bowel diseases based on their microbiome markers, according researchers from APC Microbiome Ireland. Read ‘Important’ microbiome studies offer hope for IBD prediction by Nikki Hancocks

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News

Could good oral health be the key to treating inflammatory bowel disease?

Posted: June 26 2020

Some conditions such as cardiovascular disease, respiratory infections, and diabetes are related to poor oral health. Now researchers from the University of Michigan (U-M) Medical and Dental School discovered that inflammatory bowel disease (IBD) that included Crohn’s disease and ulcerative colitis, may be the latest condition made worse by poor oral health. The mouse study […]

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People with inflammatory bowel disease might be at higher risk for dementia, study finds

Posted: June 25 2020

According to the researchers, their study was the first to explore IBD as a factor for dementia.   “It’s been quite a few years that we’ve known IBD is associated with depression and anxiety,” said Dr. Bing Zhang, a fellow in the gastroenterology division of the department of medicine at the University of California, San […]

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News

Targeting the gut layers in Crohn’s disease

Posted: June 25 2020

Although the landmark of Crohn’s Disease (CD) is the transmural inflammation, mucosal healing (MH), which is assessed by colonoscopy, is currently the gold standard of CD management. Transmural healing (TH) is a new concept evaluated by cross-sectional imaging (CSI) techniques, such as bowel ultrasound (US), computed tomography enterography (CTE) and magnetic resonance enterography (MRE). Little […]

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Research

The risk of rheumatoid arthritis among patients with inflammatory bowel disease

A systematic review and meta-analysis.

Abstract Background Studies have suggested that patients with inflammatory bowel disease (IBD) have an increased risk of rheumatoid arthritis (RA). However, the available data on this association are inconsistent. This meta-analysis aimed to determine the association between IBD and the risk of RA. Methods Observational studies investigating the RA risk among patients with IBD (Crohn […]

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