Assessing the Relationship of Vitamin D with Iron Status in Children with Inflammatory Bowel
Sana Syed, Ellen M Smith, Vin Tangpricha
IBD is a chronic intestinal condition which is manifested in the combination of several nutritional coordinating diseases including Vitamin D deficiencies. Vitamin D has recently been linked to iron metabolism through down-regulatory effects on hepcidin and hepcidin-stimulatory pro-inflammatory cytokines. In 2016, researchers published a study in the FASEB Journal which sought to address the claim that vitamin D may increase bioavailable iron for erythropoiesis and hemoglobin synthesis. The results suggested that this association was not overly significant. However when the analysing the data parsed by race it revealed that African Americans had 20 times higher odds of anemia compared to vitamin D insufficient non-African Americans.