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Mater Hospital providing support to pregnant women with IBD

Posted: September 30 2021

Inflammatory bowel disease (IBD) is a debilitating condition due to symptoms such as abdominal pain and diarrhoea and malnutrition due to poor absorption of nutrients. Mater Hospital has an integrated care model focused on optimising pregnancy outcomes of patients with IBD with an Australia’s first multidisciplinary IBD Fertility and Maternity Service (FMS). The service brings […]

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Research

Targeting disease pathways to treat ulcerative colitis – beyond corticosteroid use

Dr Chetan Karyekar, Compound Development Team Leader at The Janssen Pharmaceutical Companies of Johnson & Johnson (J&J), explains how targeting underlying immune pathways can open the door to effectively treating more inflammatory bowel disease (IBD) patients by reducing or eliminating the chronic use of corticosteroids.

By Dr Chetan Karyekar (Janssen) Currently, more than five million people around the world live with IBDs such as Crohn’s disease (CD) or ulcerative colitis (UC).1 The symptoms experienced by patients with UC are caused by inflammation and ulcers that occur along the mucosal lining of the large intestine and rectum and are driven by a dysregulated immune response.2 Disease onset can […]

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Personal Story

How I manage a Crohn’s disease flare

Posted: September 30 2021

By Basmah Ali   Flare-ups. In my opinion, they are the most terrifying words for a person living with Crohn’s disease. They’re unexpected and they’re always in the back of my mind. On one hand, there are some factors that I know trigger them, such as overexercising, missing and/or taking the wrong dosage of medications, lack […]

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News

Takeda Receives Approval to Manufacture and Market Alofisel in Japan

Posted: September 30 2021

– Alofisel (darvadstrocel) is the first expanded human allogeneic adipose-derived mesenchymal stem cell therapy to be approved in Japan– Alofisel provides a potential cell-mediated closure option for patients with complex perianal fistulas associated with Crohn’s disease who have shown an inadequate response to at least one existing medicinal treatment CD is a chronic inflammatory disease […]

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News

Unique imaging technology to map cells tied to inflammatory bowel disease

Posted: September 24 2021

New “maps” of hundreds of thousands of cells related to inflammatory bowel disease shed greater light on their effects on intestinal tissues through a newly utilized imaging technique called “imaging mass cytometry.” The novel findings by researchers at the Perelman School of Medicine at the University of Pennsylvania provide a possible path to better targeted […]

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News

Statins may be effective treatment for patients with ulcerative colitis

Posted: September 23 2021

By Hanae Armitage There may be good news for the nearly 1 million people battling ulcerative colitis, a type of inflammatory bowel condition with no real cure: Statins, a commonly prescribed cholesterol-lowering drug, seem to be an effective, if unexpected, treatment for the condition, according to a new Stanford Medicine study. Currently, the only lines of defense […]

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Blog

Here’s how Crohn’s disease can affect your eyes

Posted: September 17 2021

By Leandra Beabout  Some folks might experience sensitivity to light during a flare-up. But can your gut actually mess with your vision? Is there a link between Crohn’s disease and your eyes? It turns out, your body parts might be more interconnected than you think. Can Crohn’s disease really affect your eyes? For some folks, yes! Crohn’s is classified as […]

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Research

Novel mechanism links genetic defect in IBD patients to gut leakiness

UC Riverside-led study in mice and human tissue is the first to show how a disease mutation weakens barrier properties of epithelial cells lining the gut

By Iqbal Pittalwala A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier. The intestinal epithelium, a single layer […]

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Blog

5 Great nutrition apps that can help you manage IBD

Posted: September 16 2021

By Elizabeth Yun If you’re like many people with inflammatory bowel disease (IBD), you may have noticed that what you eat can directly influence how you feel. (Ever eaten a bag of trail mix and had stomach cramps the rest of the night?)  Since IBD affects the gastrointestinal (GI) tract, your diet plays an important role in keeping […]

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News

Precursor to ulcerative colitis in healthy individuals years before onset of disease

Posted: September 10 2021

By Maria Elisson Ulcerative colitis is an inflammatory bowel disease (IBD), with symptoms normally setting in between late adolescence and the age of 30. What causes it is not yet known, but there is lots to suggest that the disease is a result of an interplay between genetic and environmental factors and that gut flora […]

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