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Microbial infection impairs healing in Crohn’s disease

Posted: April 30 2021

The work was led by Dr Thaddeus Stappenbeck, Chair of the Cleveland Clinic Lerner Research Institute’s Department of Inflammation & Immunity, and also included researchers from Washington University in St. Louis, Cedars-Sinai Medical Center and Dartmouth College. Together, they found that levels of the yeast Debaryomyces hansenii — commonly found in cheese and processed meat — are higher in Crohn’s disease patients, particularly abundant […]

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Blog

What to eat to help reduce colon inflammation

Posted: April 28 2021

Medically reviewed by Sade Meeks, MS, RD — Written by Jenna Fletcher  During a Flare It is advisable for people with IBD to take the following measures with regard to their diet during a flare-up: Eat less fiber A person should choose white breads and rice over whole grain. Foods with less than 2 grams of fiber per serving are most suitable. Vegetables A person […]

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Research

Sarcopenia and vitamin D deficiency in patients with Crohn’s disease: Pathological conditions that should be linked together

Sarcopenia is a prevalent condition in patients with Crohn’s disease (CD), representing an independent predictor factor for the development of major postoperative complications.

Excerpt: Introduction Crohn’s disease (CD) is a chronic and progressive inflammatory bowel disease (IBD) that has a high impact on a patient’s quality of life. It is well known that all segments of the gastrointestinal tract can be affected by CD, mainly the terminal ileum and colon. Inflammation is generally segmental, asymmetrical, and transmural. Although […]

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Blog

Video: Transitioning from paediatric to adult IBD

Posted: April 26 2021

Watch video here. Transcript: Stephen Hanauer, MD: Welcome to this HCPLive® Peers and Perspectives® presentation entitled, “Expert Perspectives on the Optimal Management of Inflammatory Bowel Disease.” I’m Dr Stephen Hanauer, from Northwestern University in Chicago, and I’m delighted to be joined by Dr Marla Dubinsky, from the Icahn School of Medicine at Mount Sinai in New […]

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Research

Probiotic Lactobacillus acidophilus shows promise for treating inflammatory bowel disease and other intestinal inflammation disorders

Probiotic strain LA1 has a therapeutic effect that both prevents and treats intestinal inflammatory disorders caused by “leaky gut,” report researchers in The American Journal of Pathology.

Intestinal epithelial tight junctions (TJs) act as a functional and structural barrier against harmful antigens that promote intestinal inflammation in inflammatory bowel disease (IBD) and other inflammatory conditions of the gut. A defective intestinal TJ barrier, sometimes known as “leaky gut,” plays an important role in exacerbating and prolonging intestinal inflammation. New research reported in The American Journal […]

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Research

Wisdom, loneliness and your intestinal multitude

It may take guts — or more precisely, a diverse gut microbiome — to achieve wisdom and fend off loneliness. Or perhaps it’s the other way around, report UC San Diego researchers.

 By Scott LaFee. The evolving science of wisdom rests on the idea that wisdom’s defined traits correspond to distinct regions of the brain, and that greater wisdom translates into greater happiness and life satisfaction while being less wise results in opposite, negative consequences. Scientists have found in multiple studies that persons deemed to be wiser are less prone […]

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Research

Defects in a specific cell type may cause ulcerative colitis

There are many variants of "goblet cells" in the intestines and they seem to have different functions, according to a new study from the University of Gothenburg.

The entire inside of our intestines is covered by a thin layer of mucus that protects the fragile mucous membrane (mucosa) from bacteria and other microorganisms. If the microorganisms repeatedly come into contact with the intestinal mucosa, inflammation and even cell changes may result. These increase the risk of intestinal cancer. In a healthy colon, […]

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Research

Targeted opioid that hones in on inflamed tissues stops colitis pain without side effects

Study in mice points to promising treatment for pain in inflammatory bowel disease.

A targeted opioid that only treats diseased tissues and spares healthy tissues relieves pain from inflammatory bowel disease without causing side effects, according to new research published in the journal Gut. The study, led by researchers at New York University College of Dentistry and Queen’s University in Ontario, was conducted in mice with colitis, an inflammatory bowel […]

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Blog

9 Things to know before j-pouch surgery for ulcerative colitis

Posted: April 19 2021

By Natasha Lavender. Living with ulcerative colitis can make your life unpredictable, since you never know when or if diarrhea, fatigue, or abdominal pain will take over your day. You may even be considering having J-pouch surgery, an operation that allows you to eliminate stool after having your colon and large intestine removed. People with ulcerative colitis may […]

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Personal Story

This 19-year-old makeup artist is using TikTok to educate others on ulcerative colitis

Posted: April 19 2021

By Jessica Harrington I’m 19 years old and I got diagnosed with ulcerative colitis, which is a chronic inflammatory bowel disease that causes inflammation in the digestive tract, in my junior year of high school. I didn’t look sick but I had to go on a bunch of different medications and treatments — it was really trial and […]

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