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New potential therapy for Crohn’s disease in children

Posted: February 24 2021

Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn’s disease. This approach could become an alternative to biologic antibody therapies that carry many side effects, including increased risk of certain cancers. […]

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Personal Story

‘After my inflammatory bowel disease diagnosis, no one could’ve prepared me for life as a sick mom

Posted: February 24 2021

By Brooke Abbott, as told to Alison Goldman The first time I saw my son crawl at around 6 months old, he was moving across my hospital bed. I had been diagnosed with ulcerative colitis, an inflammatory bowel disease, 20 months before my son was born, but this was the moment I truly realized just how […]

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Blog

I’m a nutritionist with IBD. These are my 5 favorite foods for gut health

Posted: February 18 2021

By Alexa Federico While there’s not a singular list of foods that everyone with IBD should toss in their grocery carts (food tolerances vary across the board), there are a handful of foods that stand out as my personal favorites for great gut health. Bone broth Bone broth is a food with ancient origins. It’s made by […]

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Blog

Questions people with ulcerative colitis may have about biologics

Posted: February 18 2021

By Korin Miller For some people with ulcerative colitis, biologics are important for managing many painful symptoms, like diarrhea, abdominal pain, and fevers. First, here’s a little refresher on why these symptoms occur in the first place. Ulcerative colitis, an inflammatory bowel disease, causes inflammation and ulcers in your colon and rectum; your specific symptoms may vary depending on where […]

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News

Fungi in the gut prime immunity against infection

Posted: February 12 2021

Common fungi, often present in the gut, teach the immune system how to respond to their more dangerous relatives, according to new research from scientists at Weill Cornell Medicine. Breakdowns in this process can leave people susceptible to deadly fungal infections. The study, published Feb. 5 in Cell, reveals a new twist in the complex relationship […]

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News

Study identifies ‘Achilles heel’ of bacteria linked to Crohn’s disease

Posted: February 11 2021

In a study published Feb. 3 in Cell Host and Microbe, the investigators showed that patients with Crohn’s disease have an overabundance of a type of gut bacteria called adherent-invasive Escherichia coli (AIEC), whichpromotes inflammation in the intestine. Their experiments revealed that a metabolite produced by the bacteria interacts with immune system cells in the lining of […]

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News

Scientists switch on tissue repair in inflammatory bowel disease

Posted: February 9 2021

When functioning correctly, the immune system protects against harmful agents such as bacteria that get into the body. But in conditions such as inflammatory bowel disease (IBD), the immune system attacks the tissues that line the gut, forming ulcers and causing pain and discomfort. Nearly 3.9 million women and 3.0 million men are living with […]

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Blog

Why spending time around other living things positively affects your health

Posted: February 9 2021

By Markham Heid. How our environments rub off on us, sometimes literally Since 1989, when an American immunologist named David Strachan first introduced it, the “hygiene hypothesis” has gained attention and momentum. In its original form, the hypothesis held that early childhood exposure to germs — meaning infection- or illness-causing microbes — could protect people from […]

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Research

International perspectives on management of inflammatory bowel disease

Opinion differences and similarities between patients and physicians from the IBD GAPPS Survey.

Abstract Background Inflammatory bowel diseases (IBD), including Crohn disease (CD) and ulcerative colitis (UC), are complex disorders with multiple comorbidities. We conducted international patient and physician surveys to evaluate current experiences and perceptions of patients with CD or UC and physicians who treat IBD. Methods The IBD Global Assessment of Patient and Physician Unmet Need […]

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Research

Ulcerative colitis narrative global survey findings

The impact of living with ulcerative colitis—patients’ and physicians’ views.

Abstract Background The Ulcerative Colitis (UC) Narrative is a global patient and physician survey aimed at identifying the impact of UC and comparing and contrasting perceptions of UC burden and management approaches. Methods Surveys of patients with UC (self-reported diagnosis; n = 2100) and physicians (n = 1254) were completed across 10 countries by The […]

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