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Crippling anxiety, Crohn’s disease and utter despair (audio)

Posted: June 28 2019

Breaking Badly; How I Worried Myself Sick is her story. Georgie Dent has a candid chat with ABC Radio National presenter Patricia Karvelas in the Drawing Room. Listen to interview at https://www.abc.net.au/radionational/programs/drawingroom/georgie-dent/11229030

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News

New study helps develop treatments targeting inflammation without affecting gut function

Posted: June 28 2019

A new Crick-led study in Immunity has characterized these distinct populations, which could help scientists to develop treatments targeting inflammation while preserving healthy gut function. These two populations are akin to worker and soldier ants, playing different roles depending on their context. The ‘worker ant’ population of immune cells is found naturally in the gut and helps […]

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Research

Mass cytometry distinguishes between Crohn’s disease and Ulcerative colitis

Identification of better markers using less invasive methods would enable earlier diagnosis as well as improved monitoring and treatment of both diseases.

CD and UC can be distinguished clinically by disease location (UC is restricted to the colon, while CD can involve any part of the gastrointestinal tract) and disease phenotype (stricturing or penetrating can indicate CD), using endoscopy and imaging5. However, gathering this information can be invasive and costly, and still up to 20% of IBD […]

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News

Inflammatory bowel disease and type I diabetes increase chances of developing rheumatoid arthritis

Posted: June 18 2019

RA is a chronic inflammatory disease that affects the joints, causing pain and disability. It can also affect internal organs. RA is more common in older people, but there is also a high prevalence in young adults, adolescents and even children, and it affects women more frequently than men. IBD is an umbrella term used […]

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News

Cannabis use in inflammatory bowel disease: new surveys announced

Posted: June 18 2019

Inflammatory Bowel Disease (IBD) is an umbrella term describing chronic and relapsing inflammatory diseases of the gastrointestinal tract, including ulcerative colitis and Crohn’s disease. Affected individuals experience abdominal pain, weight loss, diarrhoea and bleeding with a high risk of developing colorectal and small bowel cancers. It is a debilitating condition that often significantly affects a […]

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News

A single gut enterotype linked to both inflammatory bowel disease and depression

Posted: June 18 2019

In 2012, Professor Jeroen Raes (VIB-KU Leuven Center for Microbiology) launched the Flemish Gut Flora Project. Sequencing fecal samples of over 3,000 healthy volunteers, Prof. Raes and his team defined the boundaries of a normal, health-associated gut microbiota. Next, the team turned to patient groups to identify microbiome alterations associated with diseases. Recently, they described […]

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News

Possible targets to help tackle Crohn’s disease

Posted: June 18 2019

The research has focused on different types of cells called macrophages, which are part of our immune system and are found in most tissues, where they patrol for potential harmful organisms and destroy them. In inflammatory diseases, like Crohn’s, macrophages mediate the inflammatory destruction of the gut. Just how the tissue reacts (inflammation or suppression) […]

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Personal Story

Illness can morph you without your consent

Posted: June 13 2019

When I was first diagnosed, I was told that Crohn’s disease was chronic. I looked that word up. Chronic: “Persisting for a long time or constantly recurring.” I shrugged, “No big deal” I thought. The idea of a long time didn’t compute when I was in my early twenties. Because “a long time” doesn’t really […]

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News

Public toilets letting us down

Posted: June 4 2019

In his 1937 essay What is a City?, historian, sociologist and architecture critic Lewis Mumford described the city as a theatre — a space in which the social drama of urban life could play out. It’s unlikely he envisioned the daily drama of parents with young children, the sick, and the weak-of-bladder looking in vain […]

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News

Sunshine may decrease risk of inflammatory bowel disease

Posted: June 4 2019

More than 800,000 people live with the two life-long disorders which make up IBD — Crohn’s Disease and ulcerative colitis. The paediatric study was based in Melbourne and led by Professor Robyn Lucas, from the ANU College of Health and Medicine. “Taking children to play outside in the sun could be life-changing,” Professor Lucas said. […]

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