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Mechanisms by which Stress Affects the Experimental and Clinical Inflammatory Bowel Disease (IBD): Role of Brain-Gut Axis


By Brzozowski, Bartosz; Mazur-Bialy, Agnieszka

Researchers have conducted a study to investigate the effect of stress on inflammatory bowel disease, which has seen to alter a so called “braingut axis”; reflecting changes in cortrophin releasing hormone, mast cells activity, neurotransmission at the atomic nerves system and intestinal barrier function. The appearance of chronic stress has been linked to the increase in permeability of the intestinal wall, leading to an increase in bacterial translocation. This increased prevalence in bacteria in the colonic tissue in addition to a suppressed immune system can lead to a negative impact on IBD.

View Source Article: Mechanisms by which Stress Affects the Experimental and Clinical Inflammatory Bowel Disease (IBD): Role of Brain-Gut Axis

Posted on: February 23 2018

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