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Crohn's & Colitis
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Large studies identify new risk genes for ulcerative colitis and IBD

By Catharine Paddock

A large study conducted by the Wellcome Trust Sanger Institute at Hinxton, has described finding a genetic link between a rare variant of a gene called ADCY7 that doubles the risk of developing ulcerative colitis. Research suggests a potential new drug targeted specifically at this gene could be a result of this finding. Another study found a further 25 new genetic links to increased IBD risk, which have already been showing promising results in managing IBD. Researchers plan to sequence the genomes of 25,000 patients with Irritable Bowel Syndrome, to discover more about the disease.

View Source Article: Large studies identify new risk genes for ulcerative colitis and IBD

Posted on: February 23 2018

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Good article. I certainly appreciate this site. Continue the good work!

I was very interested in the article "Good Vs bad bacteria - the bugs responsible for Crohn's disease". I was diagnosed with IBD 6 months ago and after a very bad reaction to Pentasa (but unproven) I was told to wait and try again when the symptoms peaked again. However, I started taking Probiotics each day and (touch wood) I have been in remission for 5 months, with high hopes. I am very interested in the research in this field.

My 16 year old daughter was diagnosed with UC in July 2016 and after 4 flare ups within 12 months and trying different medications, she was prescribed infliximab. This has been the miracle medication for her and am so thankful that she has been able to return to a "relatively normal life", enjoying school and her passion for sports again (bar 8 weekly visits to PMH for inflixmab infusions, routine colonoscopies and mezzaline daily). I had very little knowledge of UC and autoimmunie disease for that matter; and was shellshocked at how debilitating it can be. We are so grateful to have a wonderful gastro and medical team supporting my daughter and of course the impact that inflixmab has had; however know it is still early days and don't want to take anything for granted.

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