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Inflammatory bowel disease: Potential new treatment target identified

Catharine Paddock

The University of Oxford conducted a study on more than 200 patients’ with inflammatory bowel disease as well as two cohorts from phase 3 clinical trials of infliximab and golimumab. Conclusions drawn from this study suggest that a small protein involved in the inflammatory process could represent an effective target for drugs. As current methods of treatment have little to no effect on 40% of IBD patients, these proposed drugs could introduce a new way of treating the disorder. This could potentially have a substantial effect on the lifestyles of millions of patients worldwide.

Crohn’s and Colitis Australia would like to thank Medical News Today for permission to use this article.

Posted on: February 23 2018

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Good article. I certainly appreciate this site. Continue the good work!

I was very interested in the article "Good Vs bad bacteria - the bugs responsible for Crohn's disease". I was diagnosed with IBD 6 months ago and after a very bad reaction to Pentasa (but unproven) I was told to wait and try again when the symptoms peaked again. However, I started taking Probiotics each day and (touch wood) I have been in remission for 5 months, with high hopes. I am very interested in the research in this field.

My 16 year old daughter was diagnosed with UC in July 2016 and after 4 flare ups within 12 months and trying different medications, she was prescribed infliximab. This has been the miracle medication for her and am so thankful that she has been able to return to a "relatively normal life", enjoying school and her passion for sports again (bar 8 weekly visits to PMH for inflixmab infusions, routine colonoscopies and mezzaline daily). I had very little knowledge of UC and autoimmunie disease for that matter; and was shellshocked at how debilitating it can be. We are so grateful to have a wonderful gastro and medical team supporting my daughter and of course the impact that inflixmab has had; however know it is still early days and don't want to take anything for granted.

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