Skip to main content

Research

News

Inflammatory bowel disease and type I diabetes increase chances of developing rheumatoid arthritis

Posted: June 18 2019

RA is a chronic inflammatory disease that affects the joints, causing pain and disability. It can also affect internal organs. RA is more common in older people, but there is also a high prevalence in young adults, adolescents and even children, and it affects women more frequently than men. IBD is an umbrella term used […]

Read more

News

A single gut enterotype linked to both inflammatory bowel disease and depression

Posted: June 18 2019

In 2012, Professor Jeroen Raes (VIB-KU Leuven Center for Microbiology) launched the Flemish Gut Flora Project. Sequencing fecal samples of over 3,000 healthy volunteers, Prof. Raes and his team defined the boundaries of a normal, health-associated gut microbiota. Next, the team turned to patient groups to identify microbiome alterations associated with diseases. Recently, they described […]

Read more

News

Possible targets to help tackle Crohn’s disease

Posted: June 18 2019

The research has focused on different types of cells called macrophages, which are part of our immune system and are found in most tissues, where they patrol for potential harmful organisms and destroy them. In inflammatory diseases, like Crohn’s, macrophages mediate the inflammatory destruction of the gut. Just how the tissue reacts (inflammation or suppression) […]

Read more

News

Sunshine may decrease risk of inflammatory bowel disease

Posted: June 4 2019

More than 800,000 people live with the two life-long disorders which make up IBD — Crohn’s Disease and ulcerative colitis. The paediatric study was based in Melbourne and led by Professor Robyn Lucas, from the ANU College of Health and Medicine. “Taking children to play outside in the sun could be life-changing,” Professor Lucas said. […]

Read more

News

Daily pill containing gut bacteria from healthy people may help fight incurable conditions

Posted: May 27 2019

Bacteria taken from the faeces of healthy people could be used to treat Alzheimer’s, Parkinson’s and cancer, researchers claim. They hope the bacteria could one day replace potent drugs and treatments such as chemotherapy, which can cause a host of unwanted side effects. British scientists have now started the first trial to test whether taking […]

Read more

Research

Neural alterations in regions involved in cognitive and affective functions among Crohn’s disease patients

Evidence suggests that the disease may affect the mental state by altering the motor, sensory systems causing psychological stress.

Crohn’s disease (CD), one of the main phenotypes of inflammatory bowel disease (IBD), may affect any part of the gastrointestinal tract1, secretory gastrointestinal function and the immune system as well as increasing the intestinal permeability2. There is also evidence suggesting that the disease may affect the mental state by altering the motor, sensory systems causing […]

Read more

News

Onset of inflammatory bowel disease in adulthood tied to higher mortality

Posted: May 27 2019

Using the Swedish National Patient Register, the Karolinska Institutet identified patients who had developed inflammatory bowel disease (IBD), such as ulcerative colitis or Crohn’s disease, in adulthood between the years 1964 and 2014. Thanks to the Swedish civic registration number system, they were then able to cross-reference the disease data with the cause of death […]

Read more

News

Over-fed bacteria make people sick

Posted: May 22 2019

Since the end of the Second World War, along with the growing prosperity and the associated changes in lifestyle, numerous new and civilisation-related disease patterns have developed in today’s industrialised nations. Examples of the so-called “environmental diseases” are different bowel inflammations like Crohn’s disease or ulcerative colitis. Common causes include disruptions to the human microbiome, […]

Read more

Research

Estrogen receptor mediates anti-inflammatory action in Crohn’s disease

Accumulating evidence highlights the meaningful impact of estrogen receptors in physiology and pathophysiology of the colon.

Crohn’s disease (CD) is one of the inflammatory bowel disease (IBD) types characterized by chronic intestine inflammation. Although intestinal microbiota has been identified as the main factor responsible for immune response alternation in the past decade, other factors involved in CD pathogenesis, such as genetic and environmental, have been described. Etiology of CD is still […]

Read more

Research

Perseverance toward life goals can fend off depression and anxiety

People who don't give up on their goals and who have a positive outlook appear to have less anxiety and depression

“Perseverance cultivates a sense of purposefulness that can create resilience against or decrease current levels of major depressive disorder, generalized anxiety disorder and panic disorder,” said Nur Hani Zainal, MS, from The Pennsylvania State University and lead author of the study. “Looking on the bright side of unfortunate events has the same effect because people […]

Read more