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Medication & Treatment

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Cumulative doses of oral steroids associated with increased hypertension

Posted: March 24 2020

In a cohort of 71,642 patients (mean age, 51 years; 38% men; 86% white) diagnosed with one of six chronic inflammatory diseases — inflammatory bowel disease, rheumatoid arthritis, polymyalgia rheumatica, giant cell arteritis, vasculitis or systemic lupus erythematosus — 34.8% developed hypertension during a median follow-up of 6.6 years. Researchers found that compared with periods of nonuse, […]

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Antidepressants could ease pain for sufferers of inflammatory bowel disease

Posted: March 19 2020

Deakin University Associate Professor of Psychology Antonina Mikocka-Walus says more needed to be known about prescribing antidepressants for IBD, including for those who do not have anxiety or depression. While between 10 per cent and 30 per cent of people with IBD use antidepressants in Western countries it is unclear how many take them specifically […]

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Understanding the remission and relapse cycle in Crohn’s disease

Posted: March 17 2020

Remission Remission can mean different things based on the parameters used to describe it. Types of remission include: Clinical remission This is the term your doctor will typically use to describe your remission. It means your symptoms have improved or gone away. Yet you may still have inflammation in your GI tract. Endoscopic remission This […]

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IBD treatment algorithm should be optimised, personalised for patients

Posted: March 15 2020

“There was little we could do to alter the natural history [20 years ago],” Adam S. Cheifetz, MD, director of Center for Inflammatory Bowel Disease at Beth Israel Deaconess Medical Center and a professor of medicine at Harvard Medical School said during his presentation. “Now, where we have multiple drugs with multiple mechanisms, and many more […]

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Trial implicates MAP as treatable cause of Crohn’s disease

Posted: March 13 2020

The drug, a fixed-dose combination of clarithromycin, rifabutin and clofazimine (RHB-104, RedHill Biopharma) is yet to be approved for Crohn’s. However, the findings strengthen the case that MAP infection may be the cause of at least some cases of the disease. Infection with MAP has been a suspected, if controversial, cause of Crohn’s since the disease was […]

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Australia’s first public stool bank is paying people to donate their poo for faecal transplants

Posted: March 10 2020

Ms Wildy has been a blood donor for years, and she said donating her stool was a no-brainer. “I wanted to become a donor because I thought I was a fairly healthy person and I would have something to contribute,” she said. Ms Wildy donates about three or four times a week and said the […]

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Etrasimod offers orally delivered therapy option in UC

Posted: March 4 2020

In the study, researchers randomly assigned patients to 12 weeks of therapy with 1 mg or 2 mg once-daily etrasimod (APD334, Arena Pharmaceuticals) or placebo. Patients had a modified Mayo score between 4 and 9, endoscopic subscores of at least 2 and rectal bleeding subscores of at least 1. The primary endpoint was an increase in the […]

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Ulcerative colitis: bacteria findings raise hopes for new treatment

Posted: February 26 2020

While a number of medicines can help manage the condition, ulcerative colitis can only be cured by removing the colon. However, about half of those who have this surgery go on to have inflammation in the area of the small intestine that is reconstructed into a pouch to serve as a rectum. Such inflammation is […]

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Chronic inflammatory disease expenditures nearly double

Posted: February 18 2020

“Compared to healthy controls, we know that individuals with inflammatory bowel disease experience higher health care costs,” Benjamin Click, MD, says. “What we have also seen from prior studies is that historically, health care utilization such as hospitalizations and surgery accounted for the majority of expenditures.” To assess changes in cost of IBD care over time, Click […]

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Call for Australian government to introduce permit system for patients to grow medicinal cannabis

Posted: February 13 2020

In her submission to a Senate inquiry into barriers facing patients in accessing medicinal cannabis, Leone Harker said the current regulatory scheme was inadequate and patients should be able to grow their own cannabis plants. Ms Harker has suffered from Crohn’s disease for 16 years and has not found relief from it through the use […]

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