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Gutsy effort to produce comprehensive study of intestinal gases

Posted: September 18 2019

A source of embarrassment to some, or pure comedy to others, flatulence and the gases of the intestines are increasingly seen as playing an important role in our digestive health. A paper led by UNSW Sydney and published in Nature Reviews Gastroenterology & Hepatology has examined all available literature on gastrointestinal gases, their interactions with the microbiome […]

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Putting an end to inflammation

Posted: September 18 2019

Physician Dr. Andreas Ramming from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) has succeeded in securing research funding in one of the toughest European selection processes. Over the next five years, the European Research Council (ERC) will support his outstanding research project with an ERC Starting Grant of 1.5 million euros. Dr. Andreas Ramming from the Department of Medicine […]

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Research

Scientists discover promising new lead in Crohn’s disease

QIMR Berghofer researchers have identified a key driver of the aggressive gut disorder, Crohn’s disease, a finding that could eventually lead to new treatments for the often-debilitating condition.

Crohn’s disease – also known as inflammatory bowel disease – is incurable and affects about 35,000 people in Australia. QIMR Berghofer scientists found the protein PD-L2 was overactive in people with Crohn’s disease. The study was led by the head of the Molecular Immunology group, Dr Michelle Wykes, and Dr Graham Radford-Smith, who leads the […]

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Research

Diet-induced remission of Crohn’s disease associated with altered microbial community structure

Researchers from the University of Pennsylvania looked at the association of diet, gut microbiome and IBD.

Background The microbiome has been implicated in the initiation and persistence of inflammatory bowel disease. Despite the fact that diet is one of the most potent modulators of microbiome composition and function and that dietary intervention is the first-line therapy for treating pediatric Crohn’s disease, the relationships between diet-induced remission, enteropathy, and microbiome are poorly […]

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As CBD skyrockets in popularity, scientists scramble to understand how it’s metabolized

Posted: September 11 2019

In November of 2017, scientists at a subsidiary of Artelo Biosciences in Manchester, UK, tasked an intern with compiling any scientific study published on the body’s absorption, distribution and metabolism of cannabidiol. The company hoped to treat stroke with the compound, which is derived from the cannabis plant and commonly known as CBD, and this […]

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Drug Resistance Signature Discovered in Crohn’s Disease

Posted: September 3 2019

The study analyzed biopsy samples of inflamed and uninflamed Crohn’s disease lesions on small intestine tissue as soon as it was removed from patients. Researchers used single-cell RNA sequencing and CyTOF technology to look into the intestinal lesions in real time on a single- cellular level, identifying the immune cells and circulating blood cells and […]

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Nanoparticle relieved symptoms of inflammatory bowel disease in mice

Posted: August 28 2019

Researchers at the University of Michigan College of Pharmacy have developed a nanoparticle that alters the gut microbiome and alleviates symptoms of inflammatory bowel disease in mice more effectively than common FDA-approved medications. The gut microbiome––the body’s environment of healthy and unhealthy bacteria––is the next frontier for drug development, and an imbalanced gut microbiome has […]

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Research

Personalised medicine and genetics

Scientists have identified specific links between genes and some diseases as well as between genes and the effectiveness of some medicines or treatments.

Many of us wonder why some people develop cancer while others do not and why a medication might work well for one person but be less effective or cause serious side effects in another. Although these differences are due to a number of important factors such as age, weight and lifestyle, our genetic make-up also […]

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Research

Walnuts show ability to protect against Ulcerative colitis

Walnuts contain a complex array of natural compounds and phytochemicals that exhibit a wide range of health benefits, including protection against inflammation and colon cancer.

Dietary supplementation with nuts has shown a variety of health benefits. Among the tree nuts, walnuts (Juglans regia) contain the highest levels of the omega-3 fatty acid, namely alpha-linoleic acid (ALA), with the most favorable ratio of omega-3:omega-6 fatty acids (1:4.2) [1]. Walnuts also contain a large number of phytochemicals, including phenolic antioxidants, and high […]

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News

Smoking and ulcerative colitis

Posted: August 9 2019

Because smokers are less likely to develop ulcerative colitis (UC), a type of inflammatory bowel disease, patients with UC may be tempted to start smoking to lessen their symptoms. Researchers found no beneficial effects of smoking, however, in a nationwide study that included 6,754 patients with UC. Read full article at https://www.news-medical.net/news/20190807/Study-evaluates-the-effect-of-smoking-status-on-disease-outcomes-in-ulcerative-colitis.aspx

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