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About Crohn’s Disease

Crohn’s disease is a chronic inflammatory condition that most commonly affects the last segment of the small intestine (ileum) and the first part of the large intestine (caecum), although it can occur in any part of the GIT from the mouth to the anus. It is not uncommon for people with Crohn’s disease to have normal, healthy parts of tissue in between areas of inflammation. This has implications for how Crohn’s disease is treated, especially by surgery. Also, unlike ulcerative colitis, where the inflammation is limited to the innermost lining of the intestinal wall, in Crohn’s disease the inflammation can extend into the deeper layers, which can lead to the development of complications that are quite specific to the condition.

How does Crohn’s disease affect the intestines?

Crohn’s disease affects the GI tract, and the intestinal wall becomes inflamed (red and swollen). The inflammation can penetrate through all layers of the GI tract and may occur at one or more locations in the GI tract, from the mouth right through to the anus, with areas of normal tissue between areas of diseased tissue. Depending on the main areas of the intestine involved in Crohn’s disease, the condition can be referred to as:

  • Ileocolitis: involves the ileum and colon (small and large intestine)
  • Ileitis: involves the ileum only (small intestine only)
  • Crohn’s (granulomatous) colitis: involves the colon only (large intestine only)
  • Gastroduodenal Crohn’s disease: involves the stomach and duodenum (small intestine)
  • Jejunoileitis: involves the jejunum (small intestine only)

Additional Information:

The latest news and Research

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Patients with ulcerative colitis (UC) have reduced bone mineral density (BMD), regardless of steroid use, according to results from a meta-analysis.

In order to assess the relationship between UC and BMD, the investigators collected data from 13 cross-sectional studies published before August 2019 by searching PubMed, EMBASE, and the Cochrane Library. The meta-analysis comprised 570 patients with UC and 584 control individuals. The included studies, when pooled, indicated a decrease in BMD in patients with UC on the […]

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Tahlia Giumelli reveals her private battle with Crohn’s

Posted: March 30 2020

MISS Universe Australia finalist Tahlia Giumelli had to reveal her private battle to her new boyfriend, Rabbitohs star Tom Burgess, before they began dating. Giumelli, who will compete for the prestigious crown in Bali in June, lives with Crohn’s disease, which she has battling since 2013. The 24-year-old has been dating Burgess for six months […]

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Cumulative doses of oral steroids associated with increased hypertension

Posted: March 24 2020

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What it’s really like having a disability no one can see

Posted: March 20 2020

My name is Billie and I live with a chronic invisible illness and disability. I was diagnosed with Ulcerative Colitis (UC) at the age of 20. UC is a gut condition that effects the large intestine; causing bleeding, inflammation and ulcers along the colon. Ulcerative Colitis is also under the umbrella term ‘Inflammatory Bowel Disease (IBD)’ and […]

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Antidepressants could ease pain for sufferers of inflammatory bowel disease

Posted: March 19 2020

Deakin University Associate Professor of Psychology Antonina Mikocka-Walus says more needed to be known about prescribing antidepressants for IBD, including for those who do not have anxiety or depression. While between 10 per cent and 30 per cent of people with IBD use antidepressants in Western countries it is unclear how many take them specifically […]

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Telehealth assists infection control

Posted: March 18 2020

The six-month measure is part of the government’s plan to address the pandemic, allowing eligible Australians to access essential health services from their home while in quarantine or self-isolation. It is hoped that the strategy will reduce the risk of viral exposure to vulnerable members of the community. Who is eligible for telehealth services? People […]

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