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A restoration ecology perspective on the treatment of inflammatory bowel disease


The human gut can be considered an ecosystem comprised of a community of microbes and nonliving components.

Chronic diseases are increasingly associated with disruption of this ecosystem. The science of restoration ecology was developed to restore degraded ecosystems, but its principles have not been applied widely to gut medicine, including the treatment of inflammatory bowel disease (IBD). One principle of ecological restoration is that “passive” restoration, which involves removing an ecosystem disturbance, should occur before attempting additional “active” interventions. We discuss evidence that poor diet is principle source of disturbance in IBD, and therefore requires better attention in its research and clinical care. Another restoration principle is that higher biodiversity may improve ecosystem behavior, but this idea has not been tested for its possible importance in donor stool during fecal microbiota transplants.

Read abstract here.

Download full research paper: A restoration ecology prespective on the treatment of inflammatory bowel disease

Posted on: November 28 2019

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